Results 21 to 30 of about 4,369,422 (307)

Progress and Comment on Immunotherapy of Advanced Renal Cell Carcinoma

open access: yesZhongliu Fangzhi Yanjiu, 2020
Immunotherapy has made great progress in the treatment of advanced renal cell carcinoma (RCC), since nivolumab was approved for the second-line therapy of advanced RCC.
ZHOU Li, SHENG Xi'nan
doaj   +1 more source

Direct observation of tRNA-chaperoned folding of a dynamic mRNA ensemble

open access: yesNature Communications, 2023
T-box riboswitches are multi-domain noncoding RNAs that surveil individual amino acid availabilities in most Gram-positive bacteria. T-boxes directly bind specific tRNAs, query their aminoacylation status to detect starvation, and feedback control the ...
Krishna C. Suddala   +6 more
doaj   +1 more source

Analysis of the Outcomes of Transarterial Chemoembolization as a Bridge Therapy to Liver Transplant for Hepatocellular Carcinomas: a Single-Centered Retrospective Study [PDF]

open access: yesJournal of Sharif Medical & Dental College, 2022
Objective: To determine the outcomes of transarterial chemoembolization (TACE) as a bridging therapy to liver transplant for Barcelona clinic liver cancer (BCLC) stage A hepatocellular carcinoma.
Huma Hussain   +4 more
doaj  

miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5

open access: yesCancer Cell International, 2021
Background miR-198 is involved in the formation, migration, invasion, and metastasis of various malignant cancers. However, the function and mechanism of action of miR-198 in the tumorigenesis of renal cell carcinoma (RCC) remain elusive.
Chao Yuan   +16 more
doaj   +1 more source

Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge

open access: yesJournal of Lipid Research, 2010
Farnesoid X receptor (FXR) is a nuclear receptor that regulates genes involved in synthesis, metabolism, and transport of bile acids and thus plays a major role in maintaining bile acid homeostasis.
Joo-Youn Cho   +7 more
doaj   +1 more source

Basic Research in Kidney Cancer [PDF]

open access: yesEuropean Urology, 2011
AbstractContextAdvances in basic research will enhance prognosis, diagnosis, and treatment of renal cancer patients.ObjectiveTo discuss advances in our understanding of the molecular basis of renal cancer, targeted therapies, renal cancer and immunity, and genetic factors and renal cell carcinoma (RCC).Evidence acquisitionData on recently published ...
Pouliot, Frederic   +9 more
openaire   +4 more sources

The Year in Review for Renal Cancer [PDF]

open access: yes, 2020
The treatment of kidney cancer has made some remarkable strides over the last few years. Two regimens received Food and Drug Administration (FDA) approval, multiple biomarkers were reported to show promise, and further enhancement and refinement of the ...
Vaishampayan, Ulka
core   +1 more source

Atypical splicing variants in PKD1 explain most undiagnosed typical familial ADPKD

open access: yesnpj Genomic Medicine, 2023
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of kidney failure and is primarily associated with PKD1 or PKD2. Approximately 10% of patients remain undiagnosed after standard genetic testing.
Yvonne Hort   +12 more
doaj   +1 more source

Cancer of a Movable Kidney [PDF]

open access: yesThe American Journal of the Medical Sciences, 1898
n ...
openaire   +2 more sources

Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation

open access: yesCase Reports in Transplantation, 2016
Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given
Giovanni Varotti   +5 more
doaj   +1 more source

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