Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Analysis of the Outcomes of Transarterial Chemoembolization as a Bridge Therapy to Liver Transplant for Hepatocellular Carcinomas: a Single-Centered Retrospective Study [PDF]
Journal of Sharif Medical & Dental College, 2022 Objective: To determine the outcomes of transarterial chemoembolization (TACE) as a bridging therapy to liver transplant for Barcelona clinic liver cancer (BCLC) stage A hepatocellular carcinoma.
Huma Hussain +4 more
doaj
miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5
Cancer Cell International, 2021 Background miR-198 is involved in the formation, migration, invasion, and metastasis of various malignant cancers. However, the function and mechanism of action of miR-198 in the tumorigenesis of renal cell carcinoma (RCC) remain elusive.
Chao Yuan +16 more
doaj +1 more source
Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. [PDF]
, 2016 Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing.
Abu Aboud, Omran +13 more
core +2 more sources
Retrospective Evaluation of Clinical Experience With Intravenous Ascorbic Acid in Patients With Cancer. [PDF]
, 2018 BACKGROUND: Intravenous ascorbic acid (IV AA) has been used extensively in cancer patients throughout the United States. Currently, there are limited data on the safety and clinical effects of IV AA.
Bazzan, Anthony J. +4 more
core +2 more sources
Journal of Lipid Research, 2010 Farnesoid X receptor (FXR) is a nuclear receptor that regulates genes involved in synthesis, metabolism, and transport of bile acids and thus plays a major role in maintaining bile acid homeostasis.
Joo-Youn Cho +7 more
doaj +1 more source
The toxicity of cadmium and resulting hazards for human health [PDF]
, 2006 Cadmium (Cd) has been in industrial use for a long period of time. Its serious toxicity moved into scientific focus during the middle of the last century.
Brandenburg, Paul +6 more
core +2 more sources
Differences between physicians in the likelihood of referral and acceptance of elderly patients for dialysis-influence of age and comorbidity [PDF]
, 2007 BACKGROUND: Incidence of dialysis in elderly patients in the Netherlands is low compared to other countries. This study aims to assess the impact of patients' age and comorbidity on the likelihood of referral and acceptance of patients for dialysis and ...
De Jong, P.E. +5 more
core +3 more sources
Atypical splicing variants in PKD1 explain most undiagnosed typical familial ADPKD
npj Genomic Medicine, 2023 Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of kidney failure and is primarily associated with PKD1 or PKD2. Approximately 10% of patients remain undiagnosed after standard genetic testing.
Yvonne Hort +12 more
doaj +1 more source
Pan-cancer classifications of tumor histological images using deep learning [PDF]
, 2020 Histopathological images are essential for the diagnosis of cancer type and selection of optimal treatment. However, the current clinical process of manual inspection of images is time consuming and prone to intra- and inter-observer variability. Here we
Caruana, Dennis +8 more
core +1 more source