CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma. [PDF]
, 2015 BackgroundCytochrome P450 1B1 (CYP1B1) has been shown to be up-regulated in many types of cancer including renal cell carcinoma (RCC). Several reports have shown that CYP1B1 can influence the regulation of tumor development; however, its role in RCC has ...
Arichi, Naoko +14 more
core +2 more sources
Direct observation of tRNA-chaperoned folding of a dynamic mRNA ensemble
Nature Communications, 2023 T-box riboswitches are multi-domain noncoding RNAs that surveil individual amino acid availabilities in most Gram-positive bacteria. T-boxes directly bind specific tRNAs, query their aminoacylation status to detect starvation, and feedback control the ...
Krishna C. Suddala +6 more
doaj +1 more source
Analysis of the Outcomes of Transarterial Chemoembolization as a Bridge Therapy to Liver Transplant for Hepatocellular Carcinomas: a Single-Centered Retrospective Study [PDF]
Journal of Sharif Medical & Dental College, 2022 Objective: To determine the outcomes of transarterial chemoembolization (TACE) as a bridging therapy to liver transplant for Barcelona clinic liver cancer (BCLC) stage A hepatocellular carcinoma.
Huma Hussain +4 more
doaj
miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5
Cancer Cell International, 2021 Background miR-198 is involved in the formation, migration, invasion, and metastasis of various malignant cancers. However, the function and mechanism of action of miR-198 in the tumorigenesis of renal cell carcinoma (RCC) remain elusive.
Chao Yuan +16 more
doaj +1 more source
Incidental radiological finding of a renal tumour leading to the diagnosis of Birt-Hogg-Dubé syndrome [PDF]
, 2011 Birt-Hogg-Dubé (BHD) syndrome is a rare autosomal dominant condition characterised by benign tumours of the hair follicle, renal cancer, pulmonary cysts and spontaneous pneumothorax.
Dewilde, Dirk +5 more
core +1 more source
Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]
, 2017 In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core +1 more source
Journal of Lipid Research, 2010 Farnesoid X receptor (FXR) is a nuclear receptor that regulates genes involved in synthesis, metabolism, and transport of bile acids and thus plays a major role in maintaining bile acid homeostasis.
Joo-Youn Cho +7 more
doaj +1 more source
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Retrospective Evaluation of Clinical Experience With Intravenous Ascorbic Acid in Patients With Cancer. [PDF]
, 2018 BACKGROUND: Intravenous ascorbic acid (IV AA) has been used extensively in cancer patients throughout the United States. Currently, there are limited data on the safety and clinical effects of IV AA.
Bazzan, Anthony J. +4 more
core +2 more sources
Atypical splicing variants in PKD1 explain most undiagnosed typical familial ADPKD
npj Genomic Medicine, 2023 Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of kidney failure and is primarily associated with PKD1 or PKD2. Approximately 10% of patients remain undiagnosed after standard genetic testing.
Yvonne Hort +12 more
doaj +1 more source