Results 71 to 80 of about 4,369,422 (307)
Journal of Lipid Research, 2009 Pregnane X receptor (PXR) is an important nuclear receptor xenosensor that regulates the expression of metabolic enzymes and transporters involved in the metabolism of xenobiotics and endobiotics.
Joo-Youn Cho +7 more
doaj +1 more source
The effect of hypertension on the risk for kidney cancer in Korean men
, 2017 The effect of hypertension on the risk for kidney cancer in Korean men. Background: The role of hypertension as a kidney cancer risk factor remains unclear. The objectives of this study were to prospectively examine the effects of hypertension on kidney
지선하, 남정모
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Acute kidney injury in children with cancer admitted in an intensive care unit
, 2022 Objective: Evaluating the association between acute kidney injury and death in critically ill children with oncological diseases admitted in an intensive care unit (ICU). Material and Methods: Unicentric cohort study,
Giovanna Soldatelli Borsato +5 more
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists
Frontiers in Endocrinology, 2017 While peptide antagonists for the gastrin-releasing peptide receptor (BB2R), neuromedin B receptor (BB1R), and bombesin (BB) receptor subtype-3 (BRS-3) exist, there is a need to develop non-peptide small molecule inhibitors for all three BBR.
Terry W. Moody +6 more
doaj +1 more source
Risk of kidney cancer and chronic kidney disease in relation to hepatitis C virus infection
, 2011 Chronic hepatitis C virus (HCV) infection is an established cause of liver cancer, and recent studies have suggested a link with kidney cancer. The aim of this study was to evaluate risk of kidney cancer in relation to HCV infection in a nationwide ...
Duberg, Ann-Sofi, +17 more
core +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Cancer in Ireland 1994-2012: Annual Report of the National Cancer Registry
, 2014 In the most recent three years for which full data are available (2010-2012), on average about 36,000 newly diagnosed tumours were registered per year. Of these cases, just over 20,000 involved invasive cancers other than the less serious, non-melanoma ...
National Cancer Registry Ireland (NCRI)
core
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source