Results 101 to 110 of about 6,390,379 (302)

Mechanisms of calcineurin inhibitor nephrotoxicity in chronic allograft injury [PDF]

, 2012
The first successful transplantation of a human kidney was performed more than 50 years ago by Murray and colleagues in 1954 between identical twins. The success of this transplantation was due to the fact that no significant rejection occurs between ...
Ryan, Michael P., Johnston, Olwyn, Slattery, Craig, Cassidy, Hilary, McMorrow, Tara   +4 more
core  

The eGFR-C study: accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease - prospective longitudinal study in a multiethnic population [PDF]

, 2014
Background: Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority populations.
Sutton, AJ, Kevin Harris, eGFR-C study group (7648493), Khunti, Kamlesh, Brettell, Elizabeth A., Stevens, PE, Sutton, Andrew J., Claire C Sharpe, Lamb, EJ, Brettell, Elizabeth A, Cockwell, P, F. Loud (7648475), Sutton, Andrew J, P. E. Stevens (7648484), Sharpe, Claire C, Sharpe, CC, J. J. Deeks (7648466), Edmund J Lamb, Maarten W Taal, A. J. Sitch (7642292), Deeks, Jon J., R. S. Ottridge (7648478), Kamlesh Khunti, Elizabeth A Brettell, Taal, Maarten W., Khunti, K, Ottridge, Ryan, Lamb, Edmund J., Brettell, EA, Sutton, Andrew, Sharpe, Claire C., Ryan S Ottridge, Ottridge, Ryan S, ?, ?, N. Dalton (7648463), P. A. Kalra (7648472), Dalton, N, Kalra, PA, Neil Dalton, Taal, Maarten W, Taal, MW, Philip A Kalra, Sharpe, Claire C; id_orcid, Loud, F, K. Harris (75473), Tracy Higgins, Andrew J Sutton, Deeks, Jon J, Loud, Fiona, Dalton, Neil, Higgins, Tracy, Ottridge, RS, Higgins, T, Sitch, Alice J, Deeks, JJ, Sitch, AJ, M. W. Taal (7648490), T. Higgins (7648469), A. J. Sutton (7648487), Harris, Kevin, Kalra, Philip A, Paul Cockwell, Sitch, Alice J., Paul E Stevens, Ottridge, Ryan S., Harris, K, Deeks, Jonathan, Jon J Deeks, Stevens, Paul E., Sitch, Alice; id_orcid, E. J. Lamb (7648454), Kamlesh Khunti (171607), Fiona Loud, Stevens, Paul E, Kalra, Philip A., Alice J Sitch, Cockwell, Paul, P. Cockwell (7648460), Lamb, Edmund J, C. C. Sharpe (7648481), E. A. Brettell (7648457)   +80 more
core   +3 more sources

Dextromethorphan-induced serotonin syndrome leading to rhabdomyolysis and dialysis-requiring acute kidney injury: a case report and review

Renal Replacement Therapy
Background Dextromethorphan (DXM) misuse, particularly among young individuals, has risen owing to its euphoric and hallucinogenic effects. High-dose DXM ingestion can trigger serotonin syndrome, a condition characterized by psychiatric, neuromuscular ...
Kazuhiro Okamoto, Nobuhiro Hashimoto, Kaiya Ishizeki, Takamichi Nishimura, Shuzo Makino, Akito Takashima, Hiromitsu Miyakawa, Yoshiyasu Ueda, Terumasa Hayashi   +8 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Emerging key roles for P2X receptors in the kidney [PDF]

, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M., Peppiatt-Wildman, C. M., Wildman, S. S., R. E. Birch, C. M. Peppiatt-Wildman, Scott S Wildman, Schwiebert, E. M., Wildman, Scott S.P., E. M. Schwiebert, S. S. Wildman, Birch, R. E.   +10 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Chronic Kidney Disease After Liver Transplantation

, 2023
Chronic kidney disease among liver transplant recipients is common and associated with an increased mortality risk. Several risk factors and causes for the development of chronic kidney disease have been identified. They can be divided into perioperative
Concepcion, Beatrice P., Cabeza, Franco, Cabeza Rivera, Franco H., Levea, Swee-Ling L.   +3 more
core   +1 more source

Non-oliguric acute renal failure secondary to a potentially lethal dose of caffeine with acute intoxication: a case report

BMC Nephrology
Background Recently, the incidence of caffeine intoxication has been on an upward trend, with severe outcomes. However, acute kidney injury (AKI) resulting from renal pathologies secondary to caffeine intoxication is rare, and the pathophysiological ...
Ayaka Mitomo, Kunihiro Ishioka, Mitsuru Yanai, Takayasu Ohtake, Sumi Hidaka, Shuzo Kobayashi   +5 more
doaj   +1 more source

Patients with transobturator tape: a retrospective observational study of ten-year follow-up

Urogynaecologia International Journal
Stress urinary incontinence (SUI) may result from intrinsic sphincter weakness or urethral hypermobility brought on by weakened muscles in the pelvic floor that sustain the urethra and bladder.
Vineet Mishra, Smit Solanki, Rohina Aggarwal, Athulya Shajan   +3 more
doaj   +1 more source