Results 91 to 100 of about 6,390,379 (302)

Long-term clinical outcome of patients with severe atherosclerotic renal artery stenosis after percutaneous transluminal renal angioplasty

open access: yesRenal Replacement Therapy, 2018
Background In the patients with severe atherosclerotic renal artery stenosis (ARAS), the evaluation of long-term clinical outcome after percutaneous transluminal renal angioplasty (PTRA) has yet been insufficient.
Yasuhiro Mochida   +9 more
doaj   +1 more source

Monogenic kidney diseases in adults with chronic kidney disease

open access: yesDeutsches Ärzteblatt international
According to current evidence, every 10th to 11th adult with chronic kidney disease (CKD) has a monogenic disease of the kidney.This review is based on reported studies in which molecular genetic diagnostic techniques were used to investigate monogenic kidney diseases in adults with CKD.
Eble, Julian   +2 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Genome-wide association and functional follow-up reveals new loci for kidney function [PDF]

open access: yes, 2012
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and stratified for key CKD risk factors. We uncovered 6 new
Döring, Angela   +999 more
core   +2 more sources

Chronic Kidney Disease

open access: yes, 2023
This book provides a comprehensive overview of chronic kidney disease (CKD). It includes fifteen chapters over four sections on “Clinical Nephrology”, “Biomarkers and Molecular Biology”, “Hemodialysis and Transplantation”, and “Basic Research and ...

core   +1 more source

Relation between Blood Pressure Management and Renal Effects of Sodium-Glucose Cotransporter 2 Inhibitors in Diabetic Patients with Chronic Kidney Disease

open access: yesJournal of Diabetes Research, 2019
Aim. The renoprotective effect of sodium-glucose cotransporter 2 inhibitors is thought to be due, at least in part, to a decrease in blood pressure.
Kazuo Kobayashi   +24 more
doaj   +1 more source

Kidney diseases [PDF]

open access: yesClinical Chemistry and Laboratory Medicine (CCLM), 2021
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison Of Oral Iron and Iv Iron Sucrose for Treatment of Anemia in Postpartum Indian Women

open access: yesNational Journal of Community Medicine, 2012
Objectives: To determine the efficacy of intravenous iron sucrose and oral iron in anaemic postpartum women, presenting at Institute of Kidney Disease and Research Centre. Method: Descriptive case series.
Aggarwal Rohina S   +5 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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