Results 11 to 20 of about 10,805,577 (430)
Monogenic Kidney Diseases in Kidney Transplantation [PDF]
Kidney International ReportsMonogenic kidney diseases are involved in up to 15% of end-stage kidney diseases (ESKDs) in adults, and in 70 % of pediatric patients. When these disorders lead to kidney failure (KF), kidney transplantation (KT) is the preferred mode of replacement therapy.
Gillion, Valentine +8 more
openaire +6 more sources
Automatic Renal Segmentation in DCE-MRI using Convolutional Neural Networks [PDF]
arXiv, 2017 Kidney function evaluation using dynamic contrast-enhanced MRI (DCE-MRI) images could help in diagnosis and treatment of kidney diseases of children. Automatic segmentation of renal parenchyma is an important step in this process. In this paper, we propose a time and memory efficient fully automated segmentation method which achieves high segmentation ...
Haghighi, Marzieh +2 more
arxiv +3 more sources
Journal of Signal Transduction, 2011 Acute or chronic kidney injury results from various insults and pathological conditions, and is accompanied by activation of compensatory repair mechanisms. Both insults and repair mechanisms are initiated by circulating factors, whose cellular effects are mediated by activation selective signal transduction pathways.
Balakuntalam S. Kasinath, Denis Feliers
openaire +7 more sources
Porphyria and kidney diseases [PDF]
Clinical Kidney Journal, 2018 The kidneys, after the bone marrow and liver, are third in terms of the amounts of haem synthesized daily. Haem is incorporated into haemoproteins that are critical to renal physiology. In turn, disturbances in haem metabolism interfere with renal physiology and are tightly interrelated with kidney diseases.
Eric Thervet +7 more
openaire +5 more sources
KIDNEY DISEASE AND INSANITY [PDF]
American Journal of Psychiatry, 1897 n ...
Thomas P. Prout
openaire +4 more sources
Broadening horizons: the multifaceted functions of ferroptosis in kidney diseases
International Journal on Biological Sciences, 2023 Ferroptosis is an iron-dependent programmed cell death pattern that is characterized by iron overload, reactive oxygen species (ROS) accumulation and lipid peroxidation.
Q. Feng +10 more
semanticscholar +1 more source
Gut Dysbiosis and Kidney Diseases
Frontiers in Medicine, 2022 Gut dysbiosis is defined as disorders of gut microbiota and loss of barrier integrity, which are ubiquitous on pathological conditions and associated with the development of various diseases.
C. Cao, Han Zhu, Ying Yao, R. Zeng
semanticscholar +1 more source
Mitochondrial Redox Signaling and Oxidative Stress in Kidney Diseases
Biomolecules, 2021 Mitochondria are essential organelles in physiology and kidney diseases, because they produce cellular energy required to perform their function. During mitochondrial metabolism, reactive oxygen species (ROS) are produced.
Ana Karina Aranda-Rivera +3 more
semanticscholar +1 more source
The Cross-Link between Ferroptosis and Kidney Diseases
Oxidative Medicine and Cellular Longevity, 2021 Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders of the kidney in various etiologies, which significantly affect human survival and social wealth.
Jingyu Wang, Yi Liu, Yaqing Wang, Li Sun
semanticscholar +1 more source
cGAS‒STING signaling and function in metabolism and kidney diseases
Journal of Molecular Cell Biology, 2021 The cyclic GMP‒AMP synthase (cGAS)‒stimulator of interferon genes (STING) signaling pathway senses the presence of cytosolic DNA and, in turn, triggers downstream signaling to induce the expression of inflammatory and type I interferon genes in immune ...
Juli Bai, Feng Liu
semanticscholar +1 more source