Results 21 to 30 of about 14,135,306 (260)

Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines

Frontiers in Pharmacology, 2022
Kidney injuries may trigger renal fibrosis and lead to chronic kidney disease (CKD), but effective therapeutic strategies are still limited. Quercetin is a natural flavonoid widely distributed in herbal medicines.
Yi-qin Chen, Hao-Yin Chen, Qinghua Tang, Yi-Fan Li, Xu-Sheng Liu, Fu-hua Lu, Yueqin Gu   +6 more
semanticscholar   +1 more source

Gut Dysbiosis and Kidney Diseases

Frontiers in Medicine, 2022
Gut dysbiosis is defined as disorders of gut microbiota and loss of barrier integrity, which are ubiquitous on pathological conditions and associated with the development of various diseases.
C. Cao, Han Zhu, Ying Yao, R. Zeng
semanticscholar   +1 more source

Estrogen and estrogen receptors in kidney diseases

Renal Failure, 2021
Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney.
Hao-Yang Ma, Shuang Chen, Yang Du
semanticscholar   +1 more source

Mechanism and application of metformin in kidney diseases: An update.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Metformin is an oral antihyperglycemic drug widely used to treat type 2 diabetes mellitus (T2DM), acting via indirect activation of 5' Adenosine monophosphate-activated Protein Kinase (AMPK).
A. Song, Chun Zhang, Xian-Fang Meng
semanticscholar   +1 more source

Kidney diseases

Immunological Reviews, 2022
Dysregulation and accelerated activation of the alternative pathway (AP) of complement is known to cause or accentuate several pathologic conditions in which kidney injury leads to the appearance of hematuria and proteinuria and ultimately to the ...
E. Daina, Monica Cortinovis, Giuseppe Remuzzi   +2 more
semanticscholar   +1 more source

The Cross-Link between Ferroptosis and Kidney Diseases

Oxidative Medicine and Cellular Longevity, 2021
Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders of the kidney in various etiologies, which significantly affect human survival and social wealth.
Jing-Yu Wang, Yi Liu, Ya-Qing Wang, Li Sun   +3 more
semanticscholar   +1 more source

Kidney Organoids: A pioneering model for kidney diseases

Translational Research: The Journal of Laboratory and Clinical Medicine, 2022
The kidney is a vital organ that regulates the bodily fluid and electrolyte homeostasis via tailored urinary excretion. Kidney injuries that cause severe or progressive chronic kidney disease have driven the growing population of patients with end-stage ...
Murat Tekguc, R. V. van Gaal, S. Uzel, N. Gupta, L. Riella, J. Lewis, Ryuji Morizane   +6 more
semanticscholar   +1 more source

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

The Lancet, 2020
Summary Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries.
B. Bikbov, Caroline A. Purcell, A. Levey, Mari Smith, Amir Abdoli, Molla Abebe, Oladimeji M. Adebayo, M. Afarideh, Sachin Agarwal, Marcela Agudelo-Botero, E. Ahmadian, Ziyad Al-Aly, V. Alipour, A. Almasi-Hashiani, R. Al-Raddadi, N. Alvis-Guzmán, S. Amini, T. Andrei, C. Andrei, Zewudu Andualem, Mina Anjomshoa, J. Arabloo, A. Ashagre, Daniel Asmelash, Zerihun Ataro, M. Atout, M. Ayanore, A. Badawi, A. Bakhtiari, S. Ballew, A. Balouchi, Maciej Banach, S. Barquera, S. Basu, Mulat Tirfie Bayih, N. Bedi, A. Bello, I. Benseñor, Ali Bijani, A. Boloor, A. Borzì, L. Cámera, J. Carrero, Félix Carvalho, F. Castro, F. Catalá-López, Alex R. Chang, K. Chin, S. Chung, Massimo Cirillo, Ewerton Cousin, L. Dandona, R. Dandona, A. Daryani, Rajat Das Gupta, F. M. Demeke, Gebre Teklemariam Demoz, D. Desta, H. Do, B. Duncan, A. Eftekhari, A. Esteghamati, Syeda Sadia Fatima, J. Fernandes, E. Fernandes, F. Fischer, M. Freitas, M. Gad, Gebreamlak Gebremedhn Gebremeskel, B. M. Gebresillassie, Birhanu Geta, M. Ghafourifard, A. Ghajar, N. Ghith, P. Gill, I. Ginawi, R. Gupta, N. Hafezi-Nejad, Arvin Haj-Mirzaian, A. Haj-Mirzaian, Ninuk Hariyani, Mehedi Hasan, Milad Hasankhani, A. Hasanzadeh, H. Hassen, Simon Iain Hay, B. Heidari, Claudiu Herțeliu, Chi Linh Hoang, M. Hosseini, M. Hostiuc, S. Irvani, S. Islam, Nader Jafari Balalami, S. James, S. Jassal, V. Jha, J. Jonas, F. Joukar, J. Jozwiak, Alia Kabir, A. Kahsay, A. Kasaeian, T. Kassa, Hagazi Gebremedhin Kassaye, Yousef S. Khader, Rovshan Khalilov, E. Khan, M. S. Khan, Y. Khang, A. Kisa, C. Kovesdy, Barthelemy Kuate Defo, G. Kumar, A. Larsson, L. Lim, Alan D. Lopez, P. Lotufo, A. Majeed, R. Malekzadeh, W. März, Anthony Masaka, H. Meheretu, T. Miazgowski, Andreea Mirica, E. Mirrakhimov, P. Mithra, B. Moazen, D. K. Mohammad, R. Mohammadpourhodki, Shafiu Mohammed, A. Mokdad, Linda Morales, Ilais Moreno Velásquez, Seyyed Meysam Mousavi, S. Mukhopadhyay, J. Nachega, Girish N. Nadkarni, J. R. Nansseu, G. Natarajan, Javad Nazari, B. Neal, R. Negoi, C. Nguyen, R. Nikbakhsh, J. Noubiap, C. Nowak, A. Olagunju, Alberto Ortiz, M. Owolabi, R. Palladino, M. Pathak, H. Poustchi, S. Prakash, N. Prasad, A. Rafiei, S. Raju, K. Ramezanzadeh, S. Rawaf, D. Rawaf, Lal B. Rawal, R. Reiner, A. Rezapour, Daniel Ribeiro, Leonardo Roever, D. Rothenbacher, G. M. Rwegerera, Seyedmohammad Saadatagah, Saeed Safari, B. Sahle, Hosni Salem, J. Sanabria, I. Santos, Arash Sarveazad, M. Sawhney, E. Schaeffner, M. I. Schmidt, A. Schutte, S. Sepanlou, M. Shaikh, Z. Sharafi, M. Sharif, Amrollah Sharifi, D. Silva, Jasvinder A. Singh, N. Singh, M. M. Sisay, A. Soheili, I. Sutradhar, B. Teklehaimanot, B. Tesfay, Getnet Teshome, J. Thakur, M. Tonelli, K. Tran, B. Tran, Candide Tran Ngoc, I. Ullah, Pascual Valdez, S. Varughese, T. Vos, L. Vu, Yasir Waheed, A. Werdecker, H. F. Wolde, A. Wondmieneh, Sarah Wulf Hanson, Tomohide Yamada, Yigizie Yeshaw, N. Yonemoto, H. Yusefzadeh, Z. Zaidi, Leila Zaki, Sojib Bin Zaman, N. Zamora, A. Zarghi, Kaleab Alemayehu Zewdie, J. Ärnlöv, J. Coresh, N. Perico, G. Remuzzi, C. Murray   +221 more
semanticscholar   +1 more source

cGAS‒STING signaling and function in metabolism and kidney diseases

Journal of Molecular Cell Biology, 2021
The cyclic GMP‒AMP synthase (cGAS)‒stimulator of interferon genes (STING) signaling pathway senses the presence of cytosolic DNA and, in turn, triggers downstream signaling to induce the expression of inflammatory and type I interferon genes in immune ...
Ju-Li Bai, Feng Liu
semanticscholar   +1 more source

Recent Advances in Diabetic Kidney Diseases: From Kidney Injury to Kidney Fibrosis

International Journal of Molecular Sciences, 2021
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-stage renal disease. The natural history of DKD includes glomerular hyperfiltration, progressive albuminuria, declining estimated glomerular filtration rate, and ...
Peir-Haur Hung, Yung-Chien Hsu, Tsung-Hsien Chen, Chun-Liang Lin   +3 more
semanticscholar   +1 more source