Results 21 to 30 of about 1,448,860 (303)

Chronic Kidney Disease

open access: yesDisease-a-Month, 2015
In his review article in the March 2015 edition ofCME, Prof. A M Meyers refers to chronic kidneydisease as 'an important disease group that threatenshealth'. I fully concur with this observation andwish to go a step further and assert that kidneydisease, together with other related non-communicable diseases(NCDs), poses not only a threat to health but ...
Catherine E. Langston, Adam E. Eatroff
  +8 more sources

Vanishing kidney disease [PDF]

open access: yesBMJ Case Reports, 2013
A 60-year-old woman with a known case of diabetes mellitus for last 25 years, presented to our emergency department with symptoms of severe colicky pain in the right lumbar region and paraumbilical region of abdomen and recurrent episodes of vomiting the day before admission. Her family doctor recently moved her on to insulin as her blood sugar was not
Gopal Chandra, Ghosh   +3 more
openaire   +2 more sources

Transplantation in children [PDF]

open access: yes, 1976
Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam   +15 more
core   +1 more source

Diabetes and kidney cancer: A direct or indirect association? [PDF]

open access: yes, 2010
A positive association between diabetes and kidney cancer has been reported in several investigations, but it is unclear whether diabetes or its complications account for this association.
Bahij S. Nuwayhid   +4 more
core   +2 more sources

The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

open access: yesJournal of Translational Medicine, 2023
Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen   +13 more
doaj   +1 more source

Progress of small ubiquitin-related modifiers in kidney diseases

open access: yesChinese Medical Journal, 2019
. Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li   +6 more
doaj   +1 more source

Insulin-Like Growth Factor Binding Proteins in Kidney Disease

open access: yesFrontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang   +4 more
doaj   +1 more source

Inhalation of mercury vapor can cause the toxic effects on rat kidney [PDF]

open access: yes, 2016
Dental amalgam has been used in dentistry as a filling material. The filler comprises mercury (Hg). It is considered one of the most important and widespread environmental pollutants, which poses a serious potential threat for the humans and animals ...
Akgul, Hayati Murat   +5 more
core   +1 more source

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

open access: yesBMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee   +4 more
doaj   +1 more source

The emerging role of cellular senescence in renal diseases [PDF]

open access: yes, 2020
Cellular senescence represents the state of irreversible cell cycle arrest during cell division. Cellular senescence not only plays a role in diverse biological events such as embryogenesis, tissue regeneration and repair, ageing and tumour occurrence ...
Alpini, Gianfranco   +12 more
core   +1 more source

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