Results 31 to 40 of about 3,539,187 (313)

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

BMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee, Michael B. Fessler, Peng Qu, Jurgen Heymann, Jeffrey B. Kopp   +4 more
doaj   +1 more source

Special Pharmacological Aspects of Kidney Diseases

, 2022
The bean-shaped kidney has diverse important functions vital for life, which requires important treatments that may save this organ of any injuries. Amongst the kidney cancers, renal cell carcinoma is the most common, associated with VHL (Von Hippel ...
Hafez, Emran
core  

NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES COMPREHENSIVE STRATEGIC PLAN AND BUDGET TO REDUCE AND ULTIMATELY ELIMINATE HEALTH DISPARITIES [PDF]

, 2002
Many diseases and disorders that disproportionately impact the health of minority populations in the United States receive high priority in NIDDK research areas.
National Institute of Diabetes, and Digestive and Kidney Diseases
core   +2 more sources

Prevalence of Drug-Related Transaminitis in Post-Renal Transplant Recipients: A Single-Center Study in Peshawar

Journal of Gandhara Medical and Dental Sciences
OBJECTIVES This study aimed to estimate the prevalence, timing, pattern, and predictors of drug-related transaminitis among kidney-transplant recipients at a tertiary center in Khyber Pakhtunkhwa, Pakistan.
Farman ullah , Irfan Mirza, Muhammad Izhar, Muhammad Younas Khan   +3 more
doaj   +1 more source

Insulin-Like Growth Factor Binding Proteins in Kidney Disease

Frontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang, Shuqiang Wang, Kun Chi, Di Wu, Quan Hong   +4 more
doaj   +1 more source

Ferroptosis and kidney disease

Nefrología (English Edition), 2020
Cell death is a finely regulated process occurring through different pathways. Regulated cell death, either through apoptosis or regulated necrosis offers the possibility of therapeutic intervention. Necroptosis and ferroptosis are among the best studied forms of regulated necrosis in the context of kidney disease.
Diego Martin-Sanchez, Miguel Fontecha-Barriuso, Julio M. Martinez-Moreno, Adrian M. Ramos, Maria D. Sanchez-Niño, Melania Guerrero-Hue, Juan A. Moreno, Alberto Ortiz, Ana B. Sanz   +8 more
openaire   +3 more sources

Therapeutic Plasma Exchange in Pediatric Kidney Disease: 23-year Experience at the Severance Children's Hospital in Korea [PDF]

, 2017
Purpose: The American Society for Apheresis provides clinical guidelines for therapeutic apheresis in adults, but there are no guidelines for children. This study aimed to analyze the effect of therapeutic plasma exchange (TPE) in pediatric patients with
이금화, 신재일, 김지홍
core   +1 more source

Forgotten double-J ureteral stents: clinical burden, complications, and predictors of encrustation in a Tertiary Care Center

African Journal of Urology
Background Forgotten double-J (DJ) ureteral stents represent a preventable complication with significant morbidity. Limited data exist on patient-level determinants and systematic risk factors in low- and middle-income countries (LMICs).
Mohammad Asad Shamsher, Sajjad Muhammad Khan Shinwari, Isar Ahmad, Muhammad Afnan, Musaddif Riaz, Ikram Khan, Uzair Rahim, Zahid Ullah Khan, Hizb ullah, Niamat Ullah   +9 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source