Results 31 to 40 of about 14,135,306 (260)

Mesenchymal stem cells and extracellular vesicles in therapy against kidney diseases

Stem cell research & therapeutics, 2021
Kidney diseases pose a threat to human health due to their rising incidence and fatality rate. In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells (MSCs) are effective and safe when used to treat kidney diseases ...
Yu-Ling Huang, Li-Na Yang
semanticscholar   +1 more source

Pyroptosis: A New Frontier in Kidney Diseases

Oxidative Medicine and Cellular Longevity, 2021
Pyroptosis is a pattern of programmed cell death that significantly differs from apoptosis and autophagy in terms of cell morphology and function. The process of pyroptosis is characterized predominantly by the formation of gasdermin protein family ...
Ke-Jia Zhang, Qi Wu, Shi-Min Jiang, Lei Ding, Chao-Xia Liu, Ming Xu, Ying Wang, Yao Zhou, Li Li   +8 more
semanticscholar   +1 more source

NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES COMPREHENSIVE STRATEGIC PLAN AND BUDGET TO REDUCE AND ULTIMATELY ELIMINATE HEALTH DISPARITIES [PDF]

, 2002
Many diseases and disorders that disproportionately impact the health of minority populations in the United States receive high priority in NIDDK research areas.
National Institute of Diabetes, and Digestive and Kidney Diseases
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Genetic kidney diseases as an underrecognized cause of chronic kidney disease: the key role of international registry reports

Clinical Kidney Journal, 2021
Inherited kidney diseases (IKDs) are among the leading causes of early-onset chronic kidney disease (CKD) and are responsible for at least 10–15% of cases of kidney replacement therapy (KRT) in adults.
R. Torra, M. Furlano, A. Ortiz, E. Ars
semanticscholar   +1 more source

Mesangioproliferative Kidney Diseases and Platelet-Derived Growth Factor-Mediated AXL Phosphorylation

, 2021
Rationale & Objective: Immunoglobulin A nephropathy (IgAN) is a common glomerular disease, with mesangial cell proliferation as a major feature. There is no disease-specific treatment. Platelet-derived growth factor (PDGF) contributes to the pathogenesis
Ebefors, Kerstin,, Bian, Q., Nyström, Jenny,, Julian, B. A., Willey, C. D., Anderson, J. C., Hall, S., Novak, L., Zhang, X. W., Novak, J., Huang, Z. Q.   +10 more
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Rationale and design of the Kidney Precision Medicine Project [PDF]

, 2021
Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous, and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate a precision-medicine approach to prevention, diagnosis, and treatment.
Tuttle, Katherine, Kidney Precision Medicine Project,, El-Achkar, Tarek M, de Boer, Ian H., Troyanskaya, Olga G., Vazquez, Miguel A., Palevsky, Paul M, Gaut, Joseph P., Azeloglu, Evren U, Hodgin, Jeffrey B, Toto, Robert D., Eadon, Michael T, O\u27Toole, John F, Troyanskaya, Olga G, Mariani, Laura H., McClelland, Robyn L., Mooney, Sean D., Brown, Keith, Mariani, Laura H, Bomback, Andrew S, El-Achkar, Tarek M., Barasch, Jonathan M., Schaub, Jennifer A, Sharma, Kumar, Balis, Ulysses G. J., Barisoni, Laura, Waikar, Sushrut S., Lienczewski, Chrysta, Moledina, Dennis G, Alpers, Charles E, Jain, Sanjay, Knight, Richard, Balis, Ulysses G J, Steck, Becky, Dagher, Pierre C, O'Toole, John F, Blank, Kristina N, Laszik, Zoltan G., Alpers, Charles E., Azeloglu, Evren U., Himmelfarb, Jonathan, O'Toole, John F., McClelland, Robyn L, Iyengar, Ravi, Kellum, John A, Kellum, John A., Dighe, Ashveena L, de Boer, Ian H, Wilson, Francis Perry, Kidney Precision Medicine Project, Toto, Robert D, Hodgin, Jeffrey B., Moledina, Dennis G., Waikar, Sushrut S, Williams, Kayleen, Rosas, Sylvia E., Kiryluk, Krzysztof, Kretzler, Matthias, Palevsky, Paul M., Sedor, John R., Sedor, John R, Rosengart, Matthew R, Hacohen, Nir, Poggio, Emilio D, Schaub, Jennifer A., Eadon, Michael T., He, Yongqun, Barasch, Jonathan M, Menez, Steven, Mooney, Sean D, Dagher, Pierre C., Sarwal, Minnie M., Vazquez, Miguel A, Tuttle, Katherine R., Dighe, Ashveena L., Rosengart, Matthew R., Parikh, Chirag R, Sarwal, Minnie M, Blank, Kristina N., Zhang, Kun, Parikh, Chirag R., Bomback, Andrew S., Gaut, Joseph P, Laszik, Zoltan G, Rosas, Sylvia E, Poggio, Emilio D., Mehl, Karla, Trujillo, Jose Manuel Monroy, Winfree, Seth, Tuttle, Katherine R, Project, Kidney Precision Medicine, Malik, Rubab, d’Agati, Vivette D, Aulisio, Mark, Rosenberg, Avi, Balderes, Olivia, Cooperman, Leslie, Dagher, Pierre, Villalobos, Pam, Fine, Derek, Alexandrov, Theodore, Dunn, Kenneth, Barasch, Jonathan, Bomback, Andrew, Jolly, Stacey, Ferkowicz, Michael, Waikar, Sushrut, Radhakrishnan, Jai, Eadon, Michael, Mcmahon, Gearoid, O’Toole, John, Barwinska, Daria, O’Toole, John F, Appelbaum, Paul, Sedor, John, Sutton, Timothy, Kudose, Satoru, Stillman, Isaac, Herlitz, Leal, Short, Samuel, Slack, Alison, Ashkar, Tarek, Balis, Ulysses GJ, Weins, Astrid, Poggio, Emilio, Rosas, Sylvia, Hoover, Paul, Kelly, Katherine, Canetta, Pietro A, Weng, Chenhua, Lecker, Stewart, Williams, Mark, Parikh, Chirag, Atta, Mohammed, John F. O’Toole, Robyn Mcclelland, Pierre C. Dagher, Charles Alpers, Samuel Short, Avi Rosenberg, Derek Fine, John R. Sedor, John Kellum, Paul Appelbaum, Jeffrey Hodgin, Jennifer Schaub, Miguel Vazquez, Sean Eddy, Matthew R. Rosengart, Rajasree Menon, Chenhua Weng, Brad Rovin, Olga G. Troyanskaya, Robert Koewler, Sean D. Mooney, Pietro A. Canetta, Sylvia E. Rosas, Astrid Weins, Katherine R. Tuttle, Daniel Hall, Francisco Sanchez, Vivette D. d’Agati, Jonathan M. Barasch, Robert D. Toto, Nancy Wang, Andrew Bomback, Olga Troyanskaya, Dennis G. Moledina, Pierre Dagher, Evren Azeloglu, Jens Hansen, Christopher Lu, Parmjeet Randhawa, Emilio Poggio, Taneisha Campbell, Lorenda Wright, Laura Mariani, Stacey Jolly, Emilio D. Poggio, Victoria Blanc, Matthew Rosengart, Yongqun He, Oliver He, Michael T. Eadon, Kun Zhang, Anna Shpigel, Christopher Park, Jack Bebiak, Jennifer A. Schaub, Roy Pinkeney, Sandy Alfano, Rubab Malik, Chirag R. Parikh, Edgar Otto, Maria Joanes, Leslie Miegs, Asra Kermani, Katherine Tuttle, Ugwuowo Ugochukwu, Francis Perry Wilson, Chirag Parikh, Michael Eadon, Daria Barwinska, Dejan Dobi, Tarek M. El-Achkar, Mark Williams, Joe Gaut, Manjeri Venkatachalam, Paul Hoover, Edith Christine Stutzke, Simon Lee, Jeffrey B. Hodgin, Michael Ferkowicz, Zach Drager, John Sedor, Jai Radhakrishnan, John Saul, Kamalanathan Sambandam, Yury Goltsev, Sylvia Rosas, Rachel Sealfon, Kenneth Dunn, Tara Sigdel, Nir Hacohen, Kumar Sharma, Mary Stefanick, Frederick Dowd, Ravi Iyengar, Samir Parikh, Ian de Boer, Mohammed Atta, Andrew Schroeder, Jose Torrealba, Dennis Moledina, Isaac Stillman, Paul M. Palevsky, Sean Mooney, Tyler Miller, Mark Aulisio, Karla Mehl, Paul Palevsky, Katherine Kelly, Chrysta Lienczewski, Ljiljana Pasa-Tolic, Ian H. de Boer, Michele Elder, Krzysztof Kiryluk, Kristina Blank, Guanshi Zhang, Evren U. Azeloglu, Becky Steck, Toto Robert, Minnie M. Sarwal, Steven Menez, Harold Park, Joseph Ardayfio, Nichole Jefferson, Randy Luciano, Kristina N. Blank, Cijang (John) He, Dusan Velickovic, Jonas Carson, Andrew S. Bomback, Catherine Campbell, Mary Kruth, Sushrut S. Waikar, Charles E. Alpers, Tarek Ashkar, Anitha Vijayan, Gearoid Mcmahon, Sanjay Jain, Kayleen Williams, Chris Anderton, Blue Lake, Laura Barisoni, Stewart Lecker, Sushrut Waikar, Laura H. Mariani, Ulysses Balis, Raghav Murugan, Keith Brown, Jose Manuel Monroy Trujillo, Theodore Alexandrov, Jessica Lukowski, Leslie Cooperman, Matthias Kretzler, Orson Moe, Pam Villalobos, Miguel A. Vazquez, Lynda Hayashi, John A. Kellum, Robyn L. McClelland, Zoltan Laszik, Richard Knight, Jonathan Barasch, Alison Slack, Shweta Bansal, Olivia Balderes, John O’Toole, Mitchell Tublin, Stacy Stull, Ulysses G.J. Balis, Minnie Sarwal, Zoltan G. Laszik, Satoru Kudose, Seth Winfree, Ashveena L. Dighe, Jonathan Himmelfarb, Ashveena Dighe, Sunny Sims-Lucas, Joseph P. Gaut, Stuart Shankland, Timothy Sutton, George (Holt) Oliver, Glenda Roberts, Leal Herlitz   +315 more
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Clinical Implication of Heat Shock Protein 70 in Kidney Disease Kidney Diseases and HSP70

, 2021
Heat shock protein (HSP) 70 has been investigated from various aspects in experimental studies, since it is the most abundant form of HSP in cells. HSP 70 is involved in response to various acute and chronic insults of kidney and also other parts of the ...
Yilmaz, Alev, Yildirim, Zeynep Nagehan Yuruk   +1 more
core   +1 more source

Kynurenine pathway in kidney diseases

Pharmacological Reports, 2021
Kidney diseases have become one of the most common health care problems. Due to a growing number of advanced aged patients with concomitant disorders the prevalence of these diseases will increase over the coming decades.
I. Zakrocka, W. Załuska
semanticscholar   +1 more source

miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies

Stem Cell Research & Therapy, 2019
Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem cells have been found to exert renal protection through a variety of mechanisms, such as regulating
Si-Yang Wang, Quan Hong, Chao-Yang Zhang, Yuan-Jun Yang, Guang-Yan Cai, Xiang-Mei Chen   +5 more
doaj   +1 more source

Targeted Drug Delivery Systems for Kidney Diseases

Frontiers in Bioengineering and Biotechnology, 2021
Kidney diseases have gradually become a global health burden. Along with the development of nanotechnology, many hybrids or nanomaterials have been utilized to promote treatment efficiency with negligible side effects.
Xiaohan Huang, Yan-Hong Ma, Yang-Yang Li, Fei Han, Wei-Qiang Lin   +4 more
semanticscholar   +1 more source