Results 11 to 20 of about 952,825 (268)
Nature Reviews Disease Primers, 2015 The kidney is arguably the most important target of microvascular damage in diabetes. A substantial proportion of individuals with diabetes will develop kidney disease owing to their disease and/or other co-morbidity, including hypertension and ageing-related nephron loss.
Thomas, Merlin C. +8 more
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Progress of small ubiquitin-related modifiers in kidney diseases
Chinese Medical Journal, 2019 . Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li +6 more
doaj +1 more source
Journal of Translational Medicine, 2023 Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen +13 more
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Trail and kidney disease [PDF]
Frontiers in Bioscience, 2009 TNF-related apoptosis-inducing ligand (TRAIL, TNFSF10) is a cytokine belonging to the TNF superfamily that has been recently linked to the pathogenesis of diabetic nephropathy. TRAIL may modulate cell survival and proliferation through interaction with two different receptors, TRAIL-R1 and TRAIL-R2, and the actions of TRAIL are regulated by three decoy
Corina, Lorz +4 more
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BMC Nephrology, 2020 Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee +4 more
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FACTORS INFLUENCING RECOVERY TIME AND HOSPITAL STAY AFTER TRANSURETHRAL RESECTION OF PROSTATE (TURP)
Journal of Gandhara Medical and Dental SciencesOBJECTIVES This study aimed to evaluate the factors influencing recovery time and the length of hospital stay (LHS) following TURP surgery. METHODOLOGY A descriptive study was conducted over 6 months in the Department of Urology at the Institute of
Allah Yar khan +4 more
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Journal of Gandhara Medical and Dental SciencesOBJECTIVES This study aimed to estimate the prevalence, timing, pattern, and predictors of drug-related transaminitis among kidney-transplant recipients at a tertiary center in Khyber Pakhtunkhwa, Pakistan.
Farman ullah +3 more
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Insulin-Like Growth Factor Binding Proteins in Kidney Disease
Frontiers in Pharmacology, 2021 The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang +4 more
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African Journal of UrologyBackground Forgotten double-J (DJ) ureteral stents represent a preventable complication with significant morbidity. Limited data exist on patient-level determinants and systematic risk factors in low- and middle-income countries (LMICs).
Mohammad Asad Shamsher +9 more
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Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source