Results 11 to 20 of about 14,135,306 (260)
The Rational Use of Complement Inhibitors in Kidney Diseases
Kidney International Reports, 2022 The development of complement inhibitors represented one of the major breakthroughs in clinical nephrology in the last decade. Complement inhibition has dramatically transformed the outcome of one of the most severe kidney diseases, the atypical ...
F. Fakhouri +3 more
semanticscholar +2 more sources
Complement-mediated kidney diseases. [PDF]
Molecular Immunology, 2020 It has long been known that the complement cascade is activated in various forms of glomerulonephritis. In many of these diseases, immune-complexes deposit in the glomeruli and activate the classical pathway.
F. Poppelaars, J. Thurman
semanticscholar +2 more sources
Common Elements in Rare Kidney Diseases: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference [PDF]
, 2017 Rare kidney diseases encompass at least 150 different conditions, most of which are inherited. Although individual rare kidney diseases raise specific issues, as a group these rare diseases can have overlapping challenges in diagnosis and treatment ...
Wheeler, DC +13 more
core +5 more sources
Signaling pathways of chronic kidney diseases, implications for therapeutics
Signal Transduction and Targeted Therapy, 2022 Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) deposition.
Q. Yuan, B. Tang, Chun Zhang
semanticscholar +1 more source
The Role of Pyroptosis in the Pathogenesis of Kidney Diseases
Kidney Diseases, 2023 Background: Recently, in addition to apoptosis and necrosis, several other forms of cell death have been discovered, such as necroptosis, autophagy, pyroptosis, and ferroptosis.
Zhuanli Zhou, Qin H Li
semanticscholar +1 more source
Broadening horizons: the multifaceted functions of ferroptosis in kidney diseases
International Journal on Biological Sciences, 2023 Ferroptosis is an iron-dependent programmed cell death pattern that is characterized by iron overload, reactive oxygen species (ROS) accumulation and lipid peroxidation.
Q. Feng +10 more
semanticscholar +1 more source
Pakistan Armed Forces Medical Journal, 2022 Objective: To determine the efficacy of Hepatitis B vaccination among the candidates of maintenance hemodialysis due to chronic kidney disease and to measure the impact of ageing and Hepatitis C infection upon immune seroconversion.
Muhammad Rashid Asghar +4 more
doaj +1 more source
Cell Death and Disease, 2023 Kidney diseases remain one of the leading causes of human death and have placed a heavy burden on the medical system. Regulated cell death contributes to the pathology of a plethora of renal diseases.
Jinghan Li +3 more
semanticscholar +1 more source
Role of C-Reactive Protein in Kidney Diseases
Kidney Diseases, 2022 Background: C-reactive protein (CRP) is an acute-phase protein and has been found to be a risk factor for acute kidney injury (AKI) and chronic kidney diseases (CKD). However, the role and mechanisms of CRP in AKI and CKD remain largely unclear. Summary:
Jia-Xiao Li +3 more
semanticscholar +1 more source
Mitochondrial Redox Signaling and Oxidative Stress in Kidney Diseases
Biomolecules, 2021 Mitochondria are essential organelles in physiology and kidney diseases, because they produce cellular energy required to perform their function. During mitochondrial metabolism, reactive oxygen species (ROS) are produced.
Ana Karina Aranda-Rivera +3 more
semanticscholar +1 more source