Results 11 to 20 of about 3,539,187 (313)
Immunological Reviews, 2022 SummaryDysregulation and accelerated activation of the alternative pathway (AP) of complement is known to cause or accentuate several pathologic conditions in which kidney injury leads to the appearance of hematuria and proteinuria and ultimately to the development of chronic renal failure.
Erica Daina +2 more
openaire +2 more sources
Pakistan Armed Forces Medical Journal, 2022 Objective: To determine the efficacy of Hepatitis B vaccination among the candidates of maintenance hemodialysis due to chronic kidney disease and to measure the impact of ageing and Hepatitis C infection upon immune seroconversion.
Muhammad Rashid Asghar +4 more
doaj +1 more source
Kidney: polycystic kidney disease [PDF]
WIREs Developmental Biology, 2014 Polycystic kidney disease (PKD) is a life‐threatening genetic disorder characterized by the presence of fluid‐filled cysts primarily in the kidneys. PKD can be inherited as autosomal recessive (ARPKD) or autosomal dominant (ADPKD) traits. Mutations in either the PKD1 or PKD2 genes, which encode polycystin 1 and polycystin 2, are the underlying cause of
Binu M, Paul, Gregory B, Vanden Heuvel
openaire +2 more sources
Kidney age, not kidney disease [PDF]
Canadian Medical Association Journal, 2018 KEY POINTS Although a variety of conditions and syndromes may affect the kidneys over either chronic or acute time frames, the term “chronic kidney disease” (CKD) is used to describe a decrease in the filtration ability of the glomerular capillaries in the kidney.
Stevens, Richard J +10 more
openaire +6 more sources
Polycystic Kidney Disease [PDF]
New England Journal of Medicine, 1989 The Polycystic Kidney Disease (PKD) is a genetic disease which is characterized by the gradual emergence of cystic lesions in the kidneys, which replace the renal parenchyma causing deterioration of its function to stage 5. The PKD is one of the causes of Chronic Kidney Disease on renal replacement therapy (RRT).
Lavie, C.J. +3 more
openaire +4 more sources
Bone Disease in Chronic Kidney Disease and Kidney Transplant
Nutrients, 2022 Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) comprises alterations in calcium, phosphorus, parathyroid hormone (PTH), Vitamin D, and fibroblast growth factor-23 (FGF-23) metabolism, abnormalities in bone turnover, mineralization, volume, linear growth or strength, and vascular calcification leading to an increase in bone fractures and ...
Bellorin-Font, Ezequiel +2 more
openaire +2 more sources
Frontiers in Immunology, 2015 CD74 (invariant MHC class II) regulates protein trafficking and is a receptor for macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT/MIF-2). CD74 expression is increased in tubular cells and/or glomerular podocytes and parietal cells in human metabolic nephropathies, polycystic kidney disease, graft rejection and kidney ...
Lara eValiño-Rivas +7 more
openaire +4 more sources
The Rational Use of Complement Inhibitors in Kidney Diseases
, 2022 The development of complement inhibitors represented one of the major breakthroughs in clinical nephrology in the last decade. Complement inhibition has dramatically transformed the outcome of one of the most severe kidney diseases, the atypical ...
Fakhouri, Fadi +7 more
core +1 more source
Is “chronic kidney disease” a disease? [PDF]
Journal of Evaluation in Clinical Practice, 2018 AbstractSeveral philosophers of medicine have attempted to answer the question “what is disease?” In current clinical practice, an umbrella term “chronic kidney disease” (CKD) encompasses a wide range of kidney health states from commonly prevalent subclinical, asymptomatic disease to rare end‐stage renal disease requiring transplant or dialysis to ...
Smart, B, Stevens, R, Verbakel, J
openaire +3 more sources
A new outlook towards kidney injuries [PDF]
, 2012 Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Mahesh Satwekar, Abhijeet Satwekar
core +1 more source