Results 11 to 20 of about 994,467 (315)

The Rational Use of Complement Inhibitors in Kidney Diseases

open access: yes, 2022
The development of complement inhibitors represented one of the major breakthroughs in clinical nephrology in the last decade. Complement inhibition has dramatically transformed the outcome of one of the most severe kidney diseases, the atypical ...
Fakhouri, Fadi   +7 more
core   +1 more source

Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis [PDF]

open access: yes, 2013
Aims: To analyze the socio-demographic and clinical characteristics of patients with adult polycystic kidney disease admitted to hemodialysis services in Northwestern Paraná state, Brazil.
Tsuneto, Luiza Tamie   +13 more
core   +1 more source

NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES COMPREHENSIVE STRATEGIC PLAN AND BUDGET TO REDUCE AND ULTIMATELY ELIMINATE HEALTH DISPARITIES [PDF]

open access: yes, 2002
Many diseases and disorders that disproportionately impact the health of minority populations in the United States receive high priority in NIDDK research areas.
National Institute of Diabetes, and Digestive and Kidney Diseases
core   +1 more source

Trail and kidney disease [PDF]

open access: yesFrontiers in Bioscience, 2009
TNF-related apoptosis-inducing ligand (TRAIL, TNFSF10) is a cytokine belonging to the TNF superfamily that has been recently linked to the pathogenesis of diabetic nephropathy. TRAIL may modulate cell survival and proliferation through interaction with two different receptors, TRAIL-R1 and TRAIL-R2, and the actions of TRAIL are regulated by three decoy
Corina, Lorz   +4 more
openaire   +2 more sources

The prevalence and identification of chronic kidney disease in Switzerland [PDF]

open access: yes, 2015
BACKGROUND: Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. Patients in early CKD stages are often asymptomatic or show non-specific symptoms.
Tomonaga, Yuki
core   +1 more source

Progress of small ubiquitin-related modifiers in kidney diseases

open access: yesChinese Medical Journal, 2019
. Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li   +6 more
doaj   +1 more source

The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

open access: yesJournal of Translational Medicine, 2023
Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen   +13 more
doaj   +1 more source

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

open access: yesBMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee   +4 more
doaj   +1 more source

Insulin-Like Growth Factor Binding Proteins in Kidney Disease

open access: yesFrontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang   +4 more
doaj   +1 more source

FACTORS INFLUENCING RECOVERY TIME AND HOSPITAL STAY AFTER TRANSURETHRAL RESECTION OF PROSTATE (TURP)

open access: yesJournal of Gandhara Medical and Dental Sciences
OBJECTIVES This study aimed to evaluate the factors influencing recovery time and the length of hospital stay (LHS) following TURP surgery. METHODOLOGY A descriptive study was conducted over 6 months in the Department of Urology at the Institute of
Allah Yar khan   +4 more
doaj   +1 more source

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