Results 211 to 220 of about 952,825 (268)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

A Retrospective Study to Assess the Association Between Binge Drinking and Kidney Diseases. [PDF]

open access: yesCureus
Maramkandathil John A   +5 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Evaluation of neutrophil activation in autoimmune kidney diseases using blood heparin-binding protein: a pilot study. [PDF]

open access: yesFront Med (Lausanne)
Zhao ZJ   +9 more
europepmc   +1 more source

lncRNA TUG1 and kidney diseases. [PDF]

open access: yesBMC Nephrol
Chen T, Lu J, Fan Q.
europepmc   +1 more source

Genetics in Kidney Diseases. [PDF]

open access: yesAdv Kidney Dis Health
Yu SM, Campbell K.
europepmc   +1 more source

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