On Some of the Causes of Pericarditis, Especially Acute Rheumatism, and Bright's Disease of the Kidneys; With Incidental Observations on the Frequency and on Some of the Causes of Various other Internal Inflammations [PDF]
John S. Taylor
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Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
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Advanced Healthcare Materials, EarlyView.A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong +9 more
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Erythropoietin regulates energy metabolism through EPO-EpoR-RUNX1 axis
Nature CommunicationsErythropoietin (EPO) plays a key role in energy metabolism, with EPO receptor (EpoR) expression in white adipose tissue (WAT) mediating its metabolic activity.
Weiqin Yin +7 more
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Kidney Diseases, Urinary Deposits, and Calculous Disorders; their Nature and Treatment [PDF]
EGINA I. SADIKOVA R
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Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
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Estimand framework development for eGFR slope estimation and comparative analyses across various estimation methods [PDF]
arXivChronic kidney disease (CKD) is a global health challenge characterized by progressive kidney function decline, often culminating in end-stage kidney disease (ESKD) and increased mortality. To address the limitations such as the extended trial follow-up necessitated by the low incidence of kidney composite endpoint, the eGFR slope -- a surrogate ...
arxiv
II. Removal by Abdominal Section of a Large Sarcoma of the Kidney, Which had Undergone Extensive Cystic Degeneration. Recovery from the Operation. Rapid Recurrence of the Disease [PDF]
, 1887 C. T. CULLINGWORTH, W. Bruce Clarke
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