Results 251 to 260 of about 1,448,860 (303)

The Endothelial Glycocalyx: The First Line of Defense in the Prevention and Treatment of Kidney Diseases. [PDF]

Kidney Med
Yuan X, Jia M, Zhou L, Hou G, Zhang B, Ouyang X, Huang Y.   +6 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Fecal microbiota transplantation is a promising therapy for kidney diseases. [PDF]

Front Med (Lausanne)
Zhang J, Ren X, Li B, Zhao Z, Li S, Zhai W.   +5 more
europepmc   +1 more source

Polycystic kidney disease

Kidney International, 1982
openaire   +2 more sources

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Osteocalcin as a predictor of bone fracture in children with chronic kidney diseases. [PDF]

J Nephrol
Sawires H, Abdallah S, Ramadan M, Abdel-Halim R, Ramadan Y.   +4 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Therapeutic potential of common Phytoestrogens found in traditional Chinese medicine in chronic kidney diseases. [PDF]

Front Pharmacol
Liu T, Li M.
europepmc   +1 more source

RNA therapeutics in kidney diseases: prospects and current status. [PDF]

Clin Kidney J
Schena FP, Pasculli E.
europepmc   +1 more source

CAR-T Cell Therapy for Autoimmune Kidney Diseases: Where Do We Stand Now? [PDF]

Int J Mol Sci
Kaleta B.
europepmc   +1 more source