Results 21 to 30 of about 1,494,310 (357)
BMC Nephrology, 2020 Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee +4 more
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Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis [PDF]
, 2017 Removal of renal mass stimulates anatomical and functional adaptations in the surviving nephrons, including elevations in single-nephron glomerular filtration rate (SNGFR) and tubular hypertrophy. A goal of this study is to assess the extent to which the
Edwards, Aurelie +2 more
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Diabetes and kidney cancer: A direct or indirect association? [PDF]
, 2010 A positive association between diabetes and kidney cancer has been reported in several investigations, but it is unclear whether diabetes or its complications account for this association.
Bahij S. Nuwayhid +4 more
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The Lancet, 2021 Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality that occurs commonly in the general adult population, especially in people with diabetes and hypertension. Preservation of kidney function can improve outcomes and can be achieved through non-pharmacological strategies (eg, dietary and lifestyle adjustments ...
Kalantar-Zadeh, Kamyar +4 more
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Transplantation in children [PDF]
, 1976 Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam +15 more
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Porphyria and kidney diseases [PDF]
Clinical Kidney Journal, 2018 The kidneys, after the bone marrow and liver, are third in terms of the amounts of haem synthesized daily. Haem is incorporated into haemoproteins that are critical to renal physiology. In turn, disturbances in haem metabolism interfere with renal physiology and are tightly interrelated with kidney diseases.
Eric Thervet +7 more
openaire +4 more sources
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]
, 2017 IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna +11 more
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Polycystic kidney disease [PDF]
Nature Reviews Disease Primers, 2018 Cystic kidneys are common causes of end-stage renal disease, both in children and in adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are cilia-related disorders and the two main forms of monogenic cystic kidney diseases.
Bergmann, C. +5 more
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The emerging role of cellular senescence in renal diseases [PDF]
, 2020 Cellular senescence represents the state of irreversible cell cycle arrest during cell division. Cellular senescence not only plays a role in diverse biological events such as embryogenesis, tissue regeneration and repair, ageing and tumour occurrence ...
Alpini, Gianfranco +12 more
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Chinese Medical Journal, 2021 . Background:. Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI).
Shu-Peng Lin +9 more
doaj +1 more source