Results 51 to 60 of about 295,372 (256)

Cisplatin Induced Nephrotoxicity

مجله دانشگاه علوم پزشکی بیرجند, 2014
Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi, Abbas Ali Zeraati   +1 more
doaj  

Study the activity of Tryptase And Beta 2- Microglobulin Levels In the Sera of Patients With Chronic Renal Failure And Rheumatoid Arthritis [PDF]

Kirkuk Journal of Science, 2016
This work was mainly designed to study the levels of Mast Cell Tryptase & Beta 2- Microglobulin in serum of patients with chronic renal failure (CRF), which they were in the end stage of renal disease (ESDR) depending on hemodialysis (HD) and chronic ...
Sabah H. Khorsheed, Intisar F. Mustafa, Nazar A. Naji   +2 more
doaj   +1 more source

Survival Analysis of Hemodialysis Patients [PDF]

, 2016
Survival analysis as a collection of statistical procedures for analyzing the data that its outcome variable was the time to occurrence of an event. Kaplan-Meier method is a type of survival analysis technique, this method is often called the Product ...
Ardianto, E. T. (Efri), Notobroto, H. B. (Hari), Purnomo, W. (Windhu)   +2 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effect of high normal body mass index and its trajectory on risk of new-onset hypertension among Chinese adults: a national prospective cohort study

Frontiers in Cardiovascular Medicine
BackgroundObesity or overweight is well known to be a strong risk factor for the development of hypertension. However, the association of body mass index (BMI) within the normal range and its trajectory with new-onset hypertension in adults remains ...
Hongxue Yu, Hongxue Yu, Hongxue Yu, Hongxue Yu, Hongxue Yu, Qi Gao, Qi Gao, Yuxin Lin, Yuxin Lin, Yuxin Lin, Yuxin Lin, Yuxin Lin, Fan Luo, Fan Luo, Fan Luo, Fan Luo, Fan Luo, Pingping Li, Pingping Li, Pingping Li, Pingping Li, Pingping Li, Yuping Zhang, Yuping Zhang, Yuping Zhang, Yuping Zhang, Yuping Zhang, Jiao Liu, Jiao Liu, Jiao Liu, Jiao Liu, Jiao Liu, Ruqi Xu, Yanqin Li, Yanqin Li, Yanqin Li, Yanqin Li, Yanqin Li, Licong Su, Licong Su, Licong Su, Licong Su, Licong Su   +42 more
doaj   +1 more source

Cardiorenal relationships in patients with chronic heart failure with preserved ejection fraction

Лечащий Врач, 2023
The combination of heart and kidney diseases caused by chronic heart failure and aggravated by kidney damage, called cardiorenal syndrome, is increasingly recognized as a critical pathological unit, leading to a worsening of the prognosis in patients ...
Yu. N. Panina, V. I. Vishnevsky
doaj   +1 more source

Gambaran Kadar Kreatinin Serum Pada Pasien Penyakit Ginjal Kronik Stadium 5 Non Dialisis [PDF]

, 2016
: Chronic kidney disease is a pathophysiology process with various etiology, causing a progressive decline on kidney function, and in general ends with kidney failure (stage 5).
Alfonso, A. A. (Astrid), Memah, M. F. (Maya), Mongan, A. E. (Arthur)   +2 more
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Commentary on the burden of chronic kidney disease

Ibom Medical Journal, 2012
The kidneys are two bean shaped organs situated in the abdomen that is responsible for the excretion of metabolic waste, production of hormones, and metabolism and excretion of drugs and toxins amongst others. Chronic renal failure is said to occur when
Unadike B
doaj   +1 more source

RETRACTED: Mitochondrial tRNA Mutations Associated With Essential Hypertension: From Molecular Genetics to Function

Frontiers in Cell and Developmental Biology, 2021
Essential hypertension (EH) is one of the most common cardiovascular diseases worldwide, entailing a high level of morbidity. EH is a multifactorial disease influenced by both genetic and environmental factors, including mitochondrial DNA (mtDNA ...
Yuqi Liu, Yuqi Liu, Yuqi Liu, Yuqi Liu, Yundai Chen   +4 more
doaj   +1 more source