Results 201 to 210 of about 2,803,576 (301)

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source

Correction to: Timing of urate-lowering therapy and risk of kidney failure and mortality in CKD: an application of the parametric G-formula. [PDF]

Clin Kidney J
europepmc   +1 more source

Biallelic TMEM126B Variants as a Novel Cause of Kidney Failure-Implications for Mitochondrial Genetic Testing in Nephrology: A Response Letter. [PDF]

Clin Genet
Hammond S, Connaughton DM.
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Blood Pressure Control in Adolescents With CKD and Risk of Kidney Failure in Young Adulthood. [PDF]

Kidney Med
Glenn DA, Botdorf M, Allen A, Dickinson K, Wieand K, Davies AG, Besser V, Dixon BP, Gluck C, Hammond J, Harshman L, Kallash M, Katsoufis C, Kibrom S, Kula A, Mitsnefes M, Miyashita Y, Modi Z, Patterson L, Denburg MR, Forrest CB, Zee J.   +21 more
europepmc   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

C-C motif receptor 2 is a core profibrotic factor in uremic cardiomyopathy

Disease Models & Mechanisms
Jing-Fu Bao, Bao-Cheng Guo, Jia-Ju Mo, Hongguo Zhu, Nan Jia, Fanfan Hou, Youhua Liu, Aiqing Li   +7 more
doaj   +1 more source

Development and validation of deprescribing algorithms for kidney failure using consensus development methodology. [PDF]

J Pharm Policy Pract
Zidan A, Awad K, Habib S, Alsalemi N, Elgeed H, Hamad A, Al-Malki H, Alkadi M, Elesnawi M, Babiker F, Ibrahim R, Abdul Hadi M, Awaisu A.   +12 more
europepmc   +1 more source

Hematuria and Kidney Failure in a Patient with Kidney Cancer

Kidney360
Yoko Fujita, Shiika Watanabe, Daisuke Ichikawa   +2 more
openaire   +2 more sources

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source