Results 211 to 220 of about 5,063,263 (354)

Executive Summary of ASN Kidney Health Guidance on Conservative Management in People with Kidney Failure. [PDF]

J Am Soc Nephrol
Weiss JW, Hall R, Saeed F, Callahan MB, Shaban H, ASN Kidney Health Workgroup on Conservative Kidney Management.   +5 more
europepmc   +1 more source

The Nephrotoxicity of Vancomycin. [PDF]

, 2017
Farber, John L., Filippone, Edward J., Kraft, Walter K.   +2 more
core   +2 more sources

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

Advanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu, Kexing Li, Yuge Wang, Hongyu Li, Hongyu Zhao   +4 more
wiley   +1 more source

Climate effect on the incidence of kidney failure patients in Australia. [PDF]

BMC Med
Tesfaw LM, Tiong MK, Osborne NJ, Williams GM, Darssan D.   +4 more
europepmc   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Lived Experiences of Patients With Sickle Cell Disease and Kidney Failure: Insights From a Qualitative Study. [PDF]

J Patient Exp
Alzayer H, Alabbad E, Alnasrallah B, Alqawain A, Aljishi M.   +4 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Outcomes and predictors of kidney failure in elderly patients with biopsy-proven IgA nephropathy. [PDF]

Ren Fail
Ștefan G, Petre N, Zugravu A, Stancu S.
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Association of Metabolic Dysfunction-Associated Steatotic Liver Disease and Kidney Failure in the CKD Population. [PDF]

Kidney Int Rep
Kwon JK, Kim M, Lee J, Oh JI, Koh JH, Kang MW, Cho JM, Kim SG, Huh H, Jung S, Cho S, Lee S, Kang E, Kim Y, Kim DK, Han K, Park S.   +16 more
europepmc   +1 more source