Results 51 to 60 of about 4,640,867 (405)

Impact of Kidney Failure on the Severity of COVID-19

Journal of Clinical Medicine, 2021
Background: Patients with kidney failure are at an increased risk of progression to a severe form of coronavirus disease 2019 (COVID-19) with high mortality. The current analysis was aimed to assess the impact of renal failure on the severity of COVID-19
D. Zarębska-Michaluk, J. Jaroszewicz, M. Rogalska, Beata Lorenc, M. Rorat, Anna Szymanek-Pasternak, A. Piekarska, A. Berkan-Kawińska, K. Sikorska, M. Tudrujek-Zdunek, B. Oczko-Grzesik, B. Bolewska, P. Czupryna, D. Kozielewicz, J. Kowalska, R. Podlasin, K. Kłos, W. Mazur, P. Leszczyński, B. Szetela, Katarzyna Reczko, R. Flisiak   +21 more
semanticscholar   +1 more source

Engineered circular guide RNAs boost CRISPR/Cas12a- and CRISPR/Cas13d-based DNA and RNA editing

Genome Biology, 2023
Background The CRISPR/Cas12a and CRISPR/Cas13d systems are widely used for fundamental research and hold great potential for future clinical applications.
Xin Zhang, Xinlong Wang, Jie Lv, Hongxin Huang, Jiahong Wang, Ma Zhuo, Zhihong Tan, Guanjie Huang, Jiawei Liu, Yuchen Liu, Mengrao Li, Qixiao Lin, Lian Li, Shufeng Ma, Tao Huang, Ying Lin, Xiaoyang Zhao, Zhili Rong   +17 more
doaj   +1 more source

Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymphocytes

Frontiers in Immunology, 2022
Current evidence highlights the critical role of the gut-kidney axis in the pathogenesis of IgA nephropathy (IgAN). However, few attempts have been made to explore targeted intestinal immunity therapy.
Wang Zhang, Ye Yuan, Xiang Li, Jiao Luo, Zhanmei Zhou, Lei Yu, Guobao Wang   +6 more
doaj   +1 more source

Very Low-Calorie Ketogenic Diet: A Safe and Effective Tool for Weight Loss in Patients with Obesity and Mild Kidney Failure

Nutrients, 2020
Very low-calorie ketogenic diets (VLCKD) are an effective and increasingly used tool for weight loss. Traditionally considered high protein, ketogenic diets are often looked at with concern by clinicians due to the potential harm they pose to kidney ...
Adriano Bruci, D. Tuccinardi, R. Tozzi, A. Balena, Silvia Santucci, Riccardo Frontani, S. Mariani, S. Basciani, G. Spera, L. Gnessi, C. Lubrano, Mikiko Watanabe   +11 more
semanticscholar   +1 more source

Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. [PDF]

, 2018
Patients with severely decreased glomerular filtration rate (GFR) (i.e., chronic kidney disease [CKD] G4+) are at increased risk for kidney failure, cardiovascular disease (CVD) events (including heart failure), and death.
Bansal, N, Cheung, M, Conference Participants, ., Coresh, J, Eckardt, K-U, Evans, M, Grams, ME, Heerspink, HJL, Hemmelgarn, BR, Herzog, CA, James, MT, Pollock, CA, Stevens, PE, Tamura, MK, Tonelli, MA, Wheeler, DC, Winkelmayer, WC   +16 more
core   +2 more sources

SOX9 inactivation affects the proliferation and differentiation of human lung organoids

Stem Cell Research & Therapy, 2021
Background The regulation of the transcription factor sex-determining region Y-box transcription factor 9 (SOX9) in lung development has been described in mouse, but the same principles apply to human lung development is unknown due to a lack of ...
Lian Li, Jianqi Feng, Shanshan Zhao, Zhili Rong, Ying Lin   +4 more
doaj   +1 more source

Variety and quantity of dietary insoluble fiber intake from different sources and risk of new-onset hypertension

BMC Medicine, 2023
Background The relations of the variety and quantity of different sources of dietary insoluble fibers and hypertension remain uncertain. We aimed to investigate the associations between the variety and quantity of insoluble fibers intake from six major ...
Ziliang Ye, Qimeng Wu, Sisi Yang, Yanjun Zhang, Chun Zhou, Mengyi Liu, Zhuxian Zhang, Panpan He, Yuanyuan Zhang, Rui Li, Huan Li, Chengzhang Liu, Jing Nie, Fan Fan Hou, Xianhui Qin   +14 more
doaj   +1 more source

Predicting the risks of kidney failure and death in adults with moderate to severe chronic kidney disease: multinational, longitudinal, population based, cohort study

British medical journal
Objective To train and test a super learner strategy for risk prediction of kidney failure and mortality in people with incident moderate to severe chronic kidney disease (stage G3b to G4).
Ping Liu, Simon Sawhney, U. Heide-Jørgensen, Robert R. Quinn, S. Jensen, Andrew Mclean, C. Christiansen, T. Gerds, Pietro Ravani   +8 more
semanticscholar   +1 more source

PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis [PDF]

, 2019
Sepsis‐associated acute kidney injury (AKI) is a significant problem in critically ill children and adults resulting in increased morbidity and mortality. Fundamental mechanisms contributing to sepsis‐associated AKI are poorly understood.
Bennion, Brock G, Djukovic, Danijel, Fei, Lin, Iwaki, Takuma, Liles, W. Conrad, Lynn, Jared C, Otinga, Cynthia, Raftery, Daniel, Standage, Stephen W, Stenson, Erin K, Wong, Hector R   +10 more
core   +2 more sources

Establishing a core outcome set for peritoneal dialysis : report of the SONG-PD (standardized outcomes in nephrology-peritoneal dialysis) consensus workshop [PDF]

, 2020
Outcomes reported in randomized controlled trials in peritoneal dialysis (PD) are diverse, are measured inconsistently, and may not be important to patients, families, and clinicians.
Abraham, Georgi, Abu Alfa, Ali, Anumudu, Samaya, Au, Eric, Azukaitis, Karolis, Bargman, Joanne, Baumgartf, Amanda, Bernays, Sarah, Bernier-Jean, Amelie, Blake, Peter, Boudville, Neil, Brown, Edwina, Brown, Edwina A., Brunier, Gillian, Brunier, Gillian, Butt, Zeeshan, Carter, Simon A., Chen, Jenny, Cheung, Catherine, Cho, Yeoungjee, Cho, Yeoungjee, Craig, Jonathan, Craig, Jonathan C., Crowe, Sally, Cueto Manzano, Alfonso, da Silva, Viviane Calice, Davies, Simon, Dong, Jie, Dong, Jie, Dunn, Louese, Dunning, Tony, Evangelidis, Nicole, Figueiredo, Ana, Finkelstein, Fred, Germino, Greg, Goffin, Eric, Goh, Bak Leong, Guha, Chandana, Gutman, Talia, Gutman, Talia, Hanson, Camilla, Hemmelgarn, Brenda, Howell, Martin, Htay, Htay, Hurst, Helen, Ito, Yasuhiko, Jassal, Vanita, Jha, Vivekanand, Johnson, David, Johnson, David W., Ju, Angela, Kawanishi, Hideki, Kelly, Amy, Kelly, Ayano, Kilonzo, Kajiru Gad, Kim, Yong-Lim, Krishnan, Mahesh, Lambie, Mark, Levin, Adeera, Li, Philip Kam-Tao, Lichodziejewska-Niemierko, Monika, Liew, Adrian, Logeman, Charlotte, Maner, Karine, Manera, Karine E., Mann, Neelam, Manns, Braden, Matus, Andrea, McGee, Richard, Mehrotra, Rajnish, Mehrotra, Rajnish, Mendelson, Asher, Morelle, Johann, Nadeau-Fredette, Annie-Claire, Naicker, Sarala, Naicker, Saraladevi, Nataatmadja, Melissa, Nessim, Sharon, Neu, Alicia, Neumann, Joanna, Nourse, Peter, O'Lone, Emma, Oliver, Matthew, Pecoits-Filho, Roberto, Perl, Jeffrey, Perl, Jeffrey, Quinn, Robert, Robinson, Bruce, Rutherford, Claudia, Sanabria, Mauricio Rafael, Sautenet, Benedicte, Saxena, Anjali, Scholes-Robertson, Nicole, Schreiber, Martin, Schwartz, Daniel, Sharma, Ankit, Shen, Jenny, Shen, Jenny I., Sumpton, Daniel, Sweety, Soheli Ahmed, Szeto, Cheuk-Chun, Teitelbaum, Isaac, Teixeira-Pinto, Armando, Teo, Sharon, Toffelmire, Ted, Tong, Allison, Tugwell, Peter, Van Biesen, Wim, Van, Kim Linh, Verdin, Nancy, Viecelli, Andrea, Wang, Angela Yee-Moon, Wheeler, David, Wilkie, Martin, Wilkie, Martin, Wilson, Scott, Winkelmayer, Wolfgang, Yap, Hui Kim, Yeates, Karen   +118 more
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