Results 31 to 40 of about 2,803,576 (301)

A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8 [PDF]

, 2012
Background Nephronophthisis (NPHP) as a cause of cystic kidney disease is the most common genetic cause of progressive renal failure in children and young adults.
Morahan, G., Mathew I Bellgard, Roberto A Barrero, Morahan, G, McCooke, J.K., Bellgard, MI, Jacqueline K Phillips, Ding, A., John K McCooke, Appels, R, Grant Morahan, Phillips, J.K., Justyna E Ozimek-Kulik, Phillips, JK, Bellgard, M.I., Barrero, RA, McCooke, JK, Appels, R., Barrero, R.A., Ozimek-Kulik, J.E., Rudi Appels, Alice Ding, Ozimek-Kulik, JE, Ding, A   +23 more
core   +1 more source

SOX9 inactivation affects the proliferation and differentiation of human lung organoids

Stem Cell Research & Therapy, 2021
Background The regulation of the transcription factor sex-determining region Y-box transcription factor 9 (SOX9) in lung development has been described in mouse, but the same principles apply to human lung development is unknown due to a lack of ...
Lian Li, Jianqi Feng, Shanshan Zhao, Zhili Rong, Ying Lin   +4 more
doaj   +1 more source

Pharmacology of Treatments and Managements of Acute and Chronic Kidney Failure

, 2023
This thesis describes the treatment of Acute and Chronic Kidney failure as well as it's management. Numerous illnesses and disorders have the potential to gradually or unexpectedly decrease kidney function.
Ebenezer, Tamunokuro Power
core  

Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism. [PDF]

, 2014
Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs.
John Dixon, Philips, B, Dixon, J, Lane, K, Macphee, I, Katie Lane, Barbara Philips, Iain MacPhee   +7 more
core   +1 more source

Variety and quantity of dietary insoluble fiber intake from different sources and risk of new-onset hypertension

BMC Medicine, 2023
Background The relations of the variety and quantity of different sources of dietary insoluble fibers and hypertension remain uncertain. We aimed to investigate the associations between the variety and quantity of insoluble fibers intake from six major ...
Ziliang Ye, Qimeng Wu, Sisi Yang, Yanjun Zhang, Chun Zhou, Mengyi Liu, Zhuxian Zhang, Panpan He, Yuanyuan Zhang, Rui Li, Huan Li, Chengzhang Liu, Jing Nie, Fan Fan Hou, Xianhui Qin   +14 more
doaj   +1 more source

Reduced functional measure of cardiovascular reserve predicts admission to critical care unit following kidney transplantation [PDF]

, 2013
Background: There is currently no effective preoperative assessment for patients undergoing kidney transplantation that is able to identify those at high perioperative risk requiring admission to critical care unit (CCU).
Susan Hewins, Banerjee, P, Imray, C. (Chris), Bland, R. (Rosemary), Banerjee, Prithwish, Rosemary Bland, Ting, SMS, Zehnder, D, Ting, Stephen M. S., Stephen M S Ting, Prithwish Banerjee, Hamborg, T, Hewins, Susan, Higgins, R, Zehnder, Daniel, Daniel Zehnder, Higgins, Rob, Hewins, S, Bland, R, Chris H E Imray, Thomas Hamborg, Imray, CHE, Iqbal, H. (Hasan), Hasan Iqbal, Robert Higgins, Iqbal, H, Hamborg, Thomas   +26 more
core   +2 more sources

Hemolysis and Acute Kidney Failure [PDF]

American Journal of Kidney Diseases, 2010
Deposits of iron and hemosiderosis in the kidney have been observed in diseases with intravascular hemolysis, including paroxysmal nocturnal hemoglobinuria, and valvular heart diseases and prosthetic heart valve implants. However, the decrease in kidney function associated with hemolysis caused by cardiac valvular disease or prostheses is less well ...
Qi, Qian, Karl A, Nath, Yiming, Wu, Tarek M, Daoud, Sanjeev, Sethi   +4 more
openaire   +2 more sources

Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis

Journal of Hematology & Oncology, 2023
Hyperhomocysteinemia (HHcy) is closely associated with thrombotic diseases such as myocardial infarction and stroke. Enhanced platelet activation was observed in animals and humans with HHcy.
Wenjing Lei, Zhuoliang Liu, Zhiyuan Su, Panpan Meng, Chun Zhou, Xiaomei Chen, Zheng Hu, An Xiao, Miaomiao Zhou, Liping Huang, Yiyue Zhang, Xianhui Qin, Junping Wang, Fengxin Zhu, Jing Nie   +14 more
doaj   +1 more source

TLR2/caspase-5/Panx1 pathway mediates necrosis-induced NLRP3 inflammasome activation in macrophages during acute kidney injury

Cell Death Discovery, 2022
Acute kidney injury (AKI) is characterized by necroinflammation formed by necrotic tubular epithelial cells (TECs) and interstitial inflammation. In necroinflammation, macrophages are key inflammatory cells and can be activated and polarized into ...
Chongbin Liu, Yanting Shen, Liuwei Huang, Jun Wang   +3 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source