Results 11 to 20 of about 687,778 (313)

Failure-Aware Kidney Exchange

open access: yesProceedings of the fourteenth ACM conference on Electronic commerce, 2018
Algorithmic matches in fielded kidney exchanges do not typically result in an actual transplant. We address the problem of cycles and chains in proposed matches failing after the matching algorithm has committed to them. We show that failure-aware kidney
John Dickerson (5416868)   +2 more
core   +2 more sources

Kidney and heart failure outcomes associated with SGLT2 inhibitor use [PDF]

open access: yesNature Reviews Nephrology, 2022
Chronic kidney disease (CKD) and heart failure affect many people worldwide. Despite the availability of pharmacological treatments, both diseases remain associated with considerable morbidity and mortality.
Annemarie B Van Der Aart-Van der Beek   +2 more
exaly   +2 more sources

Capacity for the management of kidney failure in the International Society of Nephrology North and East Asia region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)

open access: yesKidney International Supplements
Globally, there remain significant disparities in the capacity and quality of kidney care, as evidenced by the third edition of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA).
Winston Wing-Shing Fung   +2 more
exaly   +2 more sources

Kidney failure in Samoa [PDF]

open access: yesThe Lancet Regional Health - Western Pacific, 2020
There is limited literature on kidney disease in the Pacific Region, despite it being recognised as a leading cause of death in some Pacific Island nations. Kidney replacement therapy is only available in a handful of Pacific Islands. This paper reports the epidemiology of haemodialysis patients in Samoa.Registry data from the National Kidney ...
Malama Tafuna'i   +7 more
openaire   +3 more sources

Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis

open access: yesFrontiers in Pharmacology, 2022
Aim: Peritoneal dialysis is a common renal replacement method for end-stage renal disease. Long-term peritoneal dialysis leads to peritoneal dialysis-related peritoneal fibrosis, which leads to a cessation of treatment.
Fang Li   +9 more
doaj   +1 more source

Association of a Healthy Lifestyle, Life's Essential 8 Scores With Incident Macrovascular and Microvascular Disease Among Individuals With Type 2 Diabetes

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The association of a healthy lifestyle with the prognosis of type 2 diabetes remains uncertain. We aimed to evaluate the associations of a healthy lifestyle and a higher American Heart Association's Life's Essential 8 score with incident ...
Panpan He   +9 more
doaj   +1 more source

Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair

open access: yesNature Communications, 2022
G2/M arrest of epithelial cells leads to fibrosis with unclear mechanisms. This study identifies a protein-encoding circRNA, circBNC2, which inhibits epithelial cells G2/M arrest to prevent fibrotic maladaptive repair in damaged kidney and liver ...
Peng Wang   +10 more
doaj   +1 more source

Kidney tubular epithelial cells control interstitial fibroblast fate by releasing TNFAIP8-encapsulated exosomes

open access: yesCell Death and Disease, 2023
Kidney fibrosis, characterized by the activation and expansion of the matrix-producing fibroblasts, is the common outcome of chronic kidney disease (CKD).
Xi Liu   +8 more
doaj   +1 more source

Matrix metalloproteinase-10 protects against acute kidney injury by augmenting epidermal growth factor receptor signaling

open access: yesCell Death and Disease, 2021
Matrix metalloproteinase-10 (MMP-10) is a zinc-dependent endopeptidase involved in regulating a wide range of biologic processes, such as apoptosis, cell proliferation, and tissue remodeling.
Chengxiao Hu   +9 more
doaj   +1 more source

PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

open access: yesCell Death and Disease, 2021
Phosphatase and Tensin Homolog on chromosome Ten (PTEN) has emerged as a key protein that governs the response to kidney injury. Notably, renal adaptive repair is important for preventing acute kidney injury (AKI) to chronic kidney disease (CKD ...
Huizhen Wang   +6 more
doaj   +1 more source

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