Results 61 to 70 of about 4,640,867 (405)

Role of miRNA-671-5p in Mediating Wnt/β-Catenin-Triggered Podocyte Injury

Frontiers in Pharmacology, 2022
Podocyte injury and proteinuria are the most common features of glomerular disease, which is the leading cause of end-stage renal failure. Hyperactivated Wnt/β-catenin signaling is closely associated with podocyte injury, but the underlying mechanisms ...
Chunhong Wang, Jiafeng Liu, Xiaoyao Zhang, Qiyan Chen, Xiaoyan Bai, Xue Hong, Lili Zhou, Youhua Liu, Youhua Liu   +8 more
doaj   +1 more source

Failure-aware kidney exchange

Proceedings of the fourteenth ACM conference on Electronic commerce, 2013
Algorithmic matches in fielded kidney exchanges do not typically result in an actual transplant. We address the problem of cycles and chains in proposed matches failing after the matching algorithm has committed to them. We show that failure-aware kidney exchange can significantly increase the expected number of lives saved (i) in theory, on random ...
John P. Dickerson, Ariel D. Procaccia, Tuomas Sandholm   +2 more
openaire   +1 more source

Association Between APOL1 Genotypes and Risk of Cardiovascular Disease in MESA (Multi-Ethnic Study of Atherosclerosis). [PDF]

, 2017
BACKGROUND:APOL1 genetic variants confer an increased risk for kidney disease. Their associations with cardiovascular disease (CVD) are less certain. We aimed to compare the prevalence of subclinical CVD and incidence of atherosclerotic CVD and heart ...
Chen, Teresa K, Estrella, Michelle M, Gutierrez, Orlando M, Katz, Ronit, Kramer, Holly, Peralta, Carmen A, Post, Wendy S, Shlipak, Michael G, Wassel, Christina L   +8 more
core   +1 more source

Genomic Testing in Patients with Kidney Failure of an Unknown Cause

American Society of Nephrology. Clinical Journal
Visual Abstract Key Points Twenty-five percent of those with unexplained kidney failure have a monogenic cause. Whole genome sequencing with broad gene panel analysis is a feasible diagnostic approach in nephrology. Background The cause of kidney failure
A. Mallawaarachchi, Lindsay Fowles, Louise Wardrop, Alasdair Wood, Rosie O’Shea, E. Biros, Trudie Harris, Stephen I. Alexander, Simon Bodek, Neil Boudville, Jo Burke, Leslie Burnett, Sarah Casauria, Steve Chadban, Aron Chakera, Sam Crafter, Pei Dai, Paul de Fazio, Randall Faull, Andrew Honda, Vanessa Huntley, S. Jahan, K. Jayasinghe, Matthew D. Jose, Anna Leaver, Mandi MacShane, Evanthia O. Madelli, Kathy Nicholls, Rhonda Pawlowski, G. Rangan, P. Snelling, Jacqueline Soraru, Madhivanan Sundaram, M. Tchan, G. Valente, M. Wallis, L. Wedd, Matthew Welland, J. Whitlam, Ella J Wilkins, Hugh J. McCarthy, Cas Simons, C. Quinlan, Chirag Patel, Zornitza Stark, A. Mallett   +45 more
semanticscholar   +1 more source

Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis

Journal of Hematology & Oncology, 2023
Hyperhomocysteinemia (HHcy) is closely associated with thrombotic diseases such as myocardial infarction and stroke. Enhanced platelet activation was observed in animals and humans with HHcy.
Wenjing Lei, Zhuoliang Liu, Zhiyuan Su, Panpan Meng, Chun Zhou, Xiaomei Chen, Zheng Hu, An Xiao, Miaomiao Zhou, Liping Huang, Yiyue Zhang, Xianhui Qin, Junping Wang, Fengxin Zhu, Jing Nie   +14 more
doaj   +1 more source

Annexin A2 plays a key role in protecting against cisplatin-induced AKI through β-catenin/TFEB pathway

Cell Death Discovery, 2022
Acute kidney injury (AKI) is in high prevalence in the world. However, the therapeutic strategies for AKI are still in mystery. Studies have shown to improve autophagy and lysosomal function could inhibit AKI.
Kunyu Shen, Jinhua Miao, Qiongdan Gao, Xian Ling, Ye Liang, Qin Zhou, Qirong Song, Yuxin Luo, Qinyu Wu, Weiwei Shen, Xiaonan Wang, Xiaolong Li, Youhua Liu, Shan Zhou, Ying Tang, Lili Zhou   +15 more
doaj   +1 more source

A Primer on Kidney Transplantation: Anatomy of the Shortage [PDF]

, 2014
Kidneys are unique among the solid organs due to the combination of the low risk of living donation, the feasibility of sustaining life on dialysis for several years following kidney failure, and Medicare coverage of dialysis and transplantation for ...
Cook, Philip J., Krawiec, Kimberly D.
core   +2 more sources

When the Earth trembles in the americas: the experience of haiti and chile 2010. [PDF]

, 2010
The response of the nephrological community to the Haiti and Chile earthquakes which occurred in the first months of 2010 is described. In Haiti, renal support was organized by the Renal Disaster Relief Task Force (RDRTF) of the International Society of ...
Borniche, D, Claus, S, Correa-Rotter, R, Crestani, R, Ferir, M C, Gibney, N, Hurtado, A, Luyckx, V A, Portilla, D, Rodriguez, S, Sever, M S, Vanholder, R, Vanmassenhove, J, Wainstein, R   +13 more
core   +2 more sources

CKD Awareness Among US Adults by Future Risk of Kidney Failure.

American Journal of Kidney Diseases, 2020
RATIONALE & OBJECTIVE Persons with chronic kidney disease (CKD) are often unaware of their disease status. Efforts to improve CKD awareness may be most effective if focused on persons at highest risk for progression to kidney failure.
Chi D. Chu, C. McCulloch, Tanushree Banerjee, Meda E. Pavkov, N. R. Burrows, B. Gillespie, R. Saran, M. Shlipak, N. Powe, D. Tuot, V. Shahinian, Michael Heung, Brenda Gillespie, H. Morgenstern, William H Herman, K. Zivin, J. Bragg-Gresham, D. Steffick, Yun Han, Xiaosong Zhang, Yiting Li, Vivian Kurtz, April Wyncott, N. Powe, Chi-yuan Hsu, D. Crews, Raymond K. Hsu, K. Johansen, M. Shlipak, J. Canela, N. R. Burrows, M. Eberhardt, Juanita Mondesire, P. Patel, Meda E. Pavkov, Deborah B. Rolka, S. Saydah, S. Shrestha, L. Waller   +38 more
semanticscholar   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source