Results 71 to 80 of about 1,022,396 (355)

Exploring access to end of life care for ethnic minorities with end stage kidney disease through recruitment in action research [PDF]

, 2016
BACKGROUND: Variation in provision of palliative care in kidney services and practitioner concerns to provide equitable access led to the development of this study which focussed on the perspectives of South Asian patients and their care providers.
A Worth, C Pentheny O’Kelly De, D Coleman, E Wilkinson, Edwina Brown, Emma Wilkinson, F Murtagh, G Randhawa, Graham Warwick, Gurch Randhawa, J Kai, J Koffman, J Reit Papp Van, J Ritchie, JE Somerville, John Stoves, Ken Farrington, M Silva Gane Da, M Silva Gane Da, Maria Da Silva Gane, N Evans, P Roderick, Regina Magee, S Chandna, S Davison, S Gunda, Sue Sharman, Tahira Akhtar   +27 more
core   +3 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

U-shaped association between triglyceride-glucose index and all-cause mortality among critically ill pediatrics: a population-based retrospective cohort study

Cardiovascular Diabetology
Background Previous studies have shown that an elevated triglyceride-glucose (TyG) index was associated with all-cause mortality in both general adult individuals and critically ill adult patients.
Qi Gao, Fan Luo, Hongxue Yu, Yuxin Lin, Ruqi Xu, Pingping Li, Yuping Zhang, Jiao Liu, Licong Su, Yanqin Li   +9 more
doaj   +1 more source

KYA1797K, a Novel Small Molecule Destabilizing β-Catenin, Is Superior to ICG-001 in Protecting against Kidney Aging

Kidney Diseases, 2022
Introduction: Aged kidney is characterized by mitochondrial dysfunction, cellular senescence, and fibrogenesis. The activation of Wnt/β-catenin signaling plays an important role in the initiation of kidney aging.
Mingsheng Zhu, Xian Ling, Shan Zhou, Ping Meng, Qiyan Chen, Shuangqin Chen, Kunyu Shen, Chao Xie, Yaozhong Kong, Maosheng Wang, Lili Zhou   +10 more
doaj   +1 more source

Acute kidney injury on chronic kidney disease: From congestive heart failure to light chain deposition disease and cast nephropathy in multiple myeloma [PDF]

, 2019
Acute on chronic renal failure is a common but notably broad diagnosis. We present a 64-year-old man with a history of diastolic heart failure and chronic kidney disease, admitted for an elevated creatinine.
Cheng, Steven, Lacasse, Alexandre, Nwankwo, Christian, Shaikh, Sana   +3 more
core   +1 more source

Calciphylaxis following kidney transplantation: a case report [PDF]

, 2009
Introduction: Calciphylaxis occurring after kidney transplantation is rare and rarely reported. It results in chronic non-healing wounds and is associated with a poor prognosis and is often fatal.
Andrew R Ready, C Shapiro, H Vanbelleghem, IA Mohammed, M Angelis, Michael A Silva, MR Hayden, N Velasco, Nicholas Inston, Paul Cockwell, R Fox, Rahul Hejmadi, Rajesh Hanvesakul, Steve Mellor, SU Nigwekar, UC Brewster   +15 more
core   +4 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Sirtuin 6 is a key contributor to gender differences in acute kidney injury

Cell Death Discovery, 2023
Acute kidney injury (AKI) is rapidly increasing nowadays and at a high risk to progress into chronic kidney disease (CKD). Of note, men are more susceptive to AKI, suggesting gender differences in AKI patients.
Jinhua Miao, Jiewu Huang, Ye Liang, Yunfang Zhang, Jiemei Li, Ping Meng, Weiwei Shen, Xiaolong Li, Qinyu Wu, Xiaoxu Wang, Hongxin Niu, Ying Tang, Shan Zhou, Lili Zhou   +13 more
doaj   +1 more source

Establishing a core outcome set for peritoneal dialysis : report of the SONG-PD (standardized outcomes in nephrology-peritoneal dialysis) consensus workshop [PDF]

, 2020
Outcomes reported in randomized controlled trials in peritoneal dialysis (PD) are diverse, are measured inconsistently, and may not be important to patients, families, and clinicians.
Abraham, Georgi, Abu Alfa, Ali, Anumudu, Samaya, Au, Eric, Azukaitis, Karolis, Bargman, Joanne, Baumgartf, Amanda, Bernays, Sarah, Bernier-Jean, Amelie, Blake, Peter, Boudville, Neil, Brown, Edwina, Brown, Edwina A., Brunier, Gillian, Brunier, Gillian, Butt, Zeeshan, Carter, Simon A., Chen, Jenny, Cheung, Catherine, Cho, Yeoungjee, Cho, Yeoungjee, Craig, Jonathan, Craig, Jonathan C., Crowe, Sally, Cueto Manzano, Alfonso, da Silva, Viviane Calice, Davies, Simon, Dong, Jie, Dong, Jie, Dunn, Louese, Dunning, Tony, Evangelidis, Nicole, Figueiredo, Ana, Finkelstein, Fred, Germino, Greg, Goffin, Eric, Goh, Bak Leong, Guha, Chandana, Gutman, Talia, Gutman, Talia, Hanson, Camilla, Hemmelgarn, Brenda, Howell, Martin, Htay, Htay, Hurst, Helen, Ito, Yasuhiko, Jassal, Vanita, Jha, Vivekanand, Johnson, David, Johnson, David W., Ju, Angela, Kawanishi, Hideki, Kelly, Amy, Kelly, Ayano, Kilonzo, Kajiru Gad, Kim, Yong-Lim, Krishnan, Mahesh, Lambie, Mark, Levin, Adeera, Li, Philip Kam-Tao, Lichodziejewska-Niemierko, Monika, Liew, Adrian, Logeman, Charlotte, Maner, Karine, Manera, Karine E., Mann, Neelam, Manns, Braden, Matus, Andrea, McGee, Richard, Mehrotra, Rajnish, Mehrotra, Rajnish, Mendelson, Asher, Morelle, Johann, Nadeau-Fredette, Annie-Claire, Naicker, Sarala, Naicker, Saraladevi, Nataatmadja, Melissa, Nessim, Sharon, Neu, Alicia, Neumann, Joanna, Nourse, Peter, O'Lone, Emma, Oliver, Matthew, Pecoits-Filho, Roberto, Perl, Jeffrey, Perl, Jeffrey, Quinn, Robert, Robinson, Bruce, Rutherford, Claudia, Sanabria, Mauricio Rafael, Sautenet, Benedicte, Saxena, Anjali, Scholes-Robertson, Nicole, Schreiber, Martin, Schwartz, Daniel, Sharma, Ankit, Shen, Jenny, Shen, Jenny I., Sumpton, Daniel, Sweety, Soheli Ahmed, Szeto, Cheuk-Chun, Teitelbaum, Isaac, Teixeira-Pinto, Armando, Teo, Sharon, Toffelmire, Ted, Tong, Allison, Tugwell, Peter, Van Biesen, Wim, Van, Kim Linh, Verdin, Nancy, Viecelli, Andrea, Wang, Angela Yee-Moon, Wheeler, David, Wilkie, Martin, Wilkie, Martin, Wilson, Scott, Winkelmayer, Wolfgang, Yap, Hui Kim, Yeates, Karen   +118 more
core   +2 more sources

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source