Adaptive Evolution of the Myo6 Gene in Old World Fruit Bats (Family: Pteropodidae) [PDF]
PMCID: PMC3631194This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Nykjaer+91 more
core +6 more sources
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The Correlation Between Kidney Function Tests and Complete Blood Count in Iraqi Patients with Chronic Hypertension [PDF]
Hypertension, also known as the silent killer, is a condition that typically remains asymptomatic until it causes significant harm to the cardiovascular system.
Tamara Sami Naji+2 more
openalex +3 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Reference values of renal tubular function tests are dependent on age and kidney function
Electrolyte disorders due to tubular disorders are rare, and knowledge about validated clinical diagnostic tools such as tubular function tests is sparse.
Anneke P. Bech+2 more
doaj +1 more source
Newer renal efficiency tests and their value in diagnosis and prognosis [PDF]
It is probable that, at the present day, the function of no organ in the body is being investigated by so many methods . in the course of hospital treatment, as that of the kidney.
Watt, Andrew Melville
core
Predicting early risk of chronic kidney disease in cats using routine clinical laboratory tests and machine learning. [PDF]
BackgroundAdvanced machine learning methods combined with large sets of health screening data provide opportunities for diagnostic value in human and veterinary medicine.Hypothesis/objectivesTo derive a model to predict the risk of cats developing ...
Bradley, Richard+8 more
core +2 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
KINETIC CHANGES OF KIDNEY FUNCTION TESTS AMONG PATIENTSWITH KIDNEY FAILURE IN ROYAL MEDICAL SERVICES [PDF]
Introduction: Kidney function tests are requested to monitor the general status of kidney health in general, and particularly to assess renal failure status.
Abeele, Jaafar Abu+6 more
core +1 more source
Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio+9 more
core +1 more source