Results 61 to 70 of about 2,251,236 (331)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Relationship between Fasting Duration before Urological Surgeries and Postoperative Renal Function

مجله دانشکده پزشکی اصفهان, 2020
Background: Fasting before surgery is a necessity, but prolonged fasting can lead to serious complications such as decreased perfusion and organ dysfunction.
Kokab Basirimoghadam, Fatemeh Hosseini-Moghaddam, Mahdi Basirimoghadam, Ali Gholamzadehkafi, Huriyeh Mahyachor, Maryam Moradi   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Reference values of renal tubular function tests are dependent on age and kidney function

Physiological Reports, 2017
Electrolyte disorders due to tubular disorders are rare, and knowledge about validated clinical diagnostic tools such as tubular function tests is sparse.
Anneke P. Bech, Jack F.M. Wetzels, Tom Nijenhuis   +2 more
doaj   +1 more source

Rationale and Design of a Clinical Trial Investigating Tolvaptan Safety and Efficacy in Autosomal Dominant Polycystic Kidney Disease [PDF]

, 2017
Background: In TEMPO 3: 4, the vasopressin V2-receptor antagonist tolvaptan slowed kidney growth and function decline in autosomal dominant polycystic kidney disease (ADPKD) patients with relatively preserved kidney function.
Torres, Vicente E., Olivier Devuyst, Perrone, Ronald D, Perrone, Ronald D., Sergeyeva, Olga, Chapman, Arlene B, Olga Sergeyeva, Devuyst, Olivier, Gansevoort, Ron T, Ron T. Gansevoort, Czerwiec, Frank S., John Ouyang, Czerwiec, Frank S, Vicente E. Torres, Torres, Vicente E, Ronald D. Perrone, Jaime D. Blais, Chapman, Arlene B., Blais, Jaime D., null null, Arlene B. Chapman, Gansevoort, Ron T., Ouyang, John, Blais, Jaime D, Frank S. Czerwiec   +24 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Clinical and radiographic outcomes following salvage intervention for ureteropelvic junction obstruction

International Brazilian Journal of Urology, 2021
Purpose: We aimed to assess failure rates of salvage interventions and changes in split kidney function (SKF) following failed primary repair of ureteropelvic junction obstruction (UPJO).
Joseph J. Crivelli, Brett A. Johnson, Ryan L. Steinberg, Jeffrey C. Gahan, Jodi A. Antonelli, Allen F. Morey, Margaret S. Pearle, Jeffrey A. Cadeddu   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigating the relationship between blood lead concentrations and kidney function tests in drug abusers admitted to Babol Hospital, Iran: A short report

Chronic Diseases Journal
BACKGROUND: The amount of impurity and addition of lead in drugs has grown increasingly. This study investigated the relationship between blood lead concentrations and kidney function tests.
Sahar Akbari-Kasgari, Iraj Javadi
doaj   +1 more source