Results 71 to 80 of about 639,789 (302)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Establishment of Allogeneic Kidney Transplantation Technical System in Banna Miniature Pig Inbred Strain

Shiyan dongwu yu bijiao yixue
ObjectiveTo establish a technical system for allogeneic kidney transplantation surgery in pigs using the Banna miniature pig inbred strain, and to evaluate it through routine blood tests, liver and kidney function tests, thus providing reference data for
ZHANG Ying, PENG Ziwei, YANG Chang, WANG Jing, ZHAO Hongfang, CHEN Gen, ZHAO Hongye, WEI Hongjiang   +7 more
doaj   +1 more source

Sponge kidney [PDF]

, 1965
A case of sponge kidney associated with pyelon e phritis arisen in 39 years old man was reported. Discussions were made on its patho-histological findings and clinical pictures. 1.
巾, 拓磨, 林, 成徳, 田中, 富士子, 西井, 治子   +3 more
core  

Cell migration and chimerism after whole‐organ transplantation: The basis of graft acceptance [PDF]

, 1993
Improvements in the prevention or control of rejection of the kidney and liver have been largely interchangeable ( 1 , 2 ) and then applicable, with very little modification, to thoracic and other organs.
Demetris, AJ, Fung, JJ, Ildstad, S, Kocova, M, Murase, N, Nalesnik, M, Ramos, H, Ricordi, C, Rudert, WA, Starzl, TE, Todo, S, Trucco, M, Tzakis, A, Zeevi, A   +13 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Effect of Low Dose Dopamine on Early Graft Function in Living Unrelated Kidney Donors

Urology Journal, 2012
Purpose: To evaluate the effect of low-dose dopamine administration on the early function of the kidney in unrelated kidney donors after transplantation.Materials and Methods: In this double-blinded clinical trial, 60 adult kidney donors and 60 ...
Parisa Hosseinzadeh, Afshar Zomorrodi, Davood Aghamohammadi, Ata Mahmoodpoor, Mohammad Abravesh, Samad Golzari, Hamzeh Hosseinzadeh   +6 more
doaj  

Evaluation of Serum Gamma-Glutamyl Transferase and Ferritin in Chronic Kidney Disease: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Chronic Kidney Disease (CKD) is a leading cause of morbidity and mortality worldwide. Oxidative stress and chronic inflammation are important factors in the development of CKD.
Okram Reshmi, Laikangbam Shaini, Ngangom Arunkumar Singh, Takhell Ambam Brojen Singh, Maharabam Purnima Devi, Sangeeta Chongtham, Soibam Pritam Singh, E Emaya   +7 more
doaj   +1 more source

Masked acute rejection of the graft kidney under the recovery of native kidneys in a patient who underwent simultaneous liver and kidney transplantation

IJU Case Reports, 2020
Introduction Simultaneous liver and kidney transplantation is a life‐saving procedure for patients with liver failure and irreversible renal dysfunction.
Kodai Hattahara, Atsuro Sawada, Kaoru Sakai, Yuki Teramoto, Yuji Nakamoto, Hideaki Okajima, Toshinari Yamasaki, Takahiro Inoue, Osamu Ogawa, Takashi Kobayashi   +9 more
doaj   +1 more source

Ex vivo renal perfusion and autotransplantation in treatment of calculous disease or abdominal aortic aneurysm. [PDF]

, 1975
Two more indications are described for temporary ex vivo perfusion of kidneys with revascularization of these organs as autografts to orthotopic or heterotopic locations. One of the patients had staghorn calculi which were removed from a solitary kidney.
Belzer, Belzer, Charles G. Halgrimson, Charles W. Putnam, Corman, Creech, Dale Atkins, Debakey, Derek P. Stables, Gauke Kootstra, Guerriero, Harrison, Mehmet Haberal, Orcutt, Robert W. Beart, Ronald Pfister, Starzl, Thomas E. Starzl   +17 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source