Results 141 to 150 of about 1,061,703 (360)

Ameliorative Effects of Two Forms of Pomegranate on Glomerular Transvertical Diameter in Steroid- Induced Kidney Damage in Mice

Journal of Rawalpindi Medical College, 2017
To observe the effects of Pomegranate juice (PJ) and Pomegranate peel extract (PPE) on glomerular transvertical diameter in steroid induced mice kidney damage. Methods: In this experimental study forty healthy adult mice (BALB/c strain), average weighing
Humaira Ali
doaj  

Glomerulus-specific mRNA transcripts and proteins identified through kidney expressed sequence tag database analysis [PDF]

, 2007
Liqun He, Ying Sun, Jaakko Patrakka, Petter Mostad, Jenny Norlin, Zhijie Xiao, Johanna Andræ, Karl Tryggvason, Tore Samuelsson, Christer Betsholtz, Minoru Takemoto   +10 more
openalex   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Comparative analysis of primary and secondary glomerulopathies in the northeast of Brazil: data from the Pernambuco Registry of Glomerulopathies - REPEG

Brazilian Journal of Nephrology
Introduction: In Brazil, glomerulopathies are the third leading cause of chronic renal disease, accounting for 11% of dialysis patients. Studies on the prevalence of this disease in Northeastern Brazil are scarce.
Denise Maria do Nascimento Costa, Lucila Maria Valente, Pedro Alves da Cruz Gouveia, Filipe Wanick Sarinho, Gisele Vajgel Fernandes, Maria Alina Gomes de Mattos Cavalcante, Camila Barbosa Lyra de Oliveira, Carolina de Andrade Jordão de Vasconcelos, Emanuel Sávio Cavalcante Sarinho   +8 more
doaj   +1 more source

PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases

Advanced Science, EarlyView.
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou, Hongchao Zhu, Xiaonan Sun, Ni Zhang, Song Wang, Xuexing Zheng, Xiaoyun Wang, Yueyue Feng, Fuzhen Zhang, Xingyu Li, Rui Li, Xiaomeng Wang, Yuanyuan Han, Jun Wang, Chuanhong Wang, Xiaoyang Yao, Hongmei Wang, Hongbin He   +17 more
wiley   +1 more source

A comparative molecular approach to mesodermal patterning in basal deuterostomes: the expression pattern of Brachyury in the enteropneust hemichordate Ptychodera flava [PDF]

, 1999
This work concerns the formation of mesoderm in the development of an enteropneust hemichordate, Ptychodera flava, and the expression of the Brachyury gene during this process. Brachyury expression occurs in two distinct phases.
Cameron, R. Andrew, Davidson, Eric H., Peterson, Kevin J., Satoh, Noriyuki, Tagawa, Kunifumi   +4 more
core  

A pH‐Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury

Advanced Science, EarlyView.
A biomimetic nanoplatform (CeAst@MK) is engineered for precise therapy of acute kidney injury by integrating cerium‐based antioxidation, natural flavonoid astragalin, and macrophage membrane camouflage. Featuring kidney‐targeted and pH‐responsive release, CeAst@MK scavenges ROS, suppresses inflammation, and restores renal function via modulation of ...
Shichao Zhang, Yuhan Xie, Longchao Zhang, Yuanjiong Qi, Quan Liao, Chenglong Xu, Shushuai Yang, Haiwen Zhou, Qidan Tan, Shiyong Qi   +9 more
wiley   +1 more source

Deep-learning model for evaluating histopathology of acute renal tubular injury

Scientific Reports
Tubular injury is the most common cause of acute kidney injury. Histopathological diagnosis may help distinguish between the different types of acute kidney injury and aid in treatment.
Thi Thuy Uyen Nguyen, Anh-Tien Nguyen, Hyeongwan Kim, Yu Jin Jung, Woong Park, Kyoung Min Kim, Ilwoo Park, Won Kim   +7 more
doaj   +1 more source

ORGAN SPECIFIC VASCULAR RESPONSE TO FIBROSIS AFFECTS BREAST CANCER METASTATIC ORGANOTROPISM [PDF]

, 2016
The solid tumor microenvironment, pre-metastatic niche, and fibrotic environment are known to have significant biochemical and biomechanical similarities to the fibrotic environment. All have significantly increased levels of factors such as TGFβ, HIF1α,
Fletcher, Eliot S, Fletcher, Eliot S
core   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source