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Research into the structure of the kidney glomerulus – making it count

Micron, 2012
The renal glomerulus and its components have been intensively studied using microscopy - both light and electron - for decades and much has been learnt about their role in the pathogenesis of chronic kidney diseases such as diabetic nephropathy. In order to get more than purely qualitative information from the images, stereological tools have been ...
K. White
exaly   +4 more sources

Models of kidney glomerulus derived from human-induced pluripotent stem cells

iPSCs in Tissue Engineering, 2021
Human pluripotent stem cells hold tremendous promise for understanding tissue development and disease mechanisms, and for in vitro modeling of organ function.
Samira Musah, Rohan Bhattacharya
exaly   +2 more sources

Human kidney glomerulus proteome and biomarker discovery of kidney diseases

Proteomics - Clinical Applications, 2008
AbstractThe kidney glomerulus is the site of plasma filtration and production of primary urine in the kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but also is the locus of kidney diseases progressing to chronic renal failure.
Y. Yoshida   +7 more
exaly   +4 more sources

Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus

Biochemical and Biophysical Research Communications, 2009
Thyroglobulin (Tg) is an essential substrate for thyroid hormone biosynthesis whose production is primarily limited to the thyroid follicular cell. We have previously identified an approximately 1.2 kb fragment of Tg mRNA in cultured mouse mesangial cells, and in the present study provide evidence showing that this transcript is transcribed and ...
Koichi Suzuki   +2 more
exaly   +4 more sources

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