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Kidney International, 2007 The kidney glomerulus plays a crucial role in blood filtration but the molecular composition and physiology of the glomerulus is not well understood. We previously constructed and large-scale sequenced four mouse glomerular expressed sequence tag (EST ...
Petter Mostad, K Tryggvason
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Endothelin and the Glomerulus in Chronic Kidney Disease [PDF]
Seminars in Nephrology, 2015 Endothelin-1 (ET-1) is a 21-amino acid peptide with mitogenic and powerful vasoconstricting properties. Under healthy conditions, ET-1 is expressed constitutively in all cells of the glomerulus and participates in homeostasis of glomerular structure and filtration function.
Andrey Sorokin, Matthias Barton
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Large‐scale identification of genes implicated in kidney glomerulus development and function [PDF]
EMBO Journal, 2006 To advance our understanding of development, function and diseases in the kidney glomerulus, we have established and large-scale sequenced cDNA libraries from mouse glomeruli at different stages of development, resulting in a catalogue of 6053 different ...
Yusuke Baba +2 more
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Human kidney glomerulus proteome and biomarker discovery of kidney diseases
Proteomics - Clinical Applications, 2008AbstractThe kidney glomerulus is the site of plasma filtration and production of primary urine in the kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but also is the locus of kidney diseases progressing to chronic renal failure.
Tadashi Yamamoto +2 more
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