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Targeting Therapeutics to the Glomerulus With Nanoparticles
Advances in Chronic Kidney Disease, 2013 Nanoparticles are an enabling technology for the creation of tissue-/cell-specific therapeutics that have been investigated extensively as targeted therapeutics for cancer.
Jonathan E Zuckerman, Mark E Davis
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Large-scale identification of genes implicated in kidney glomerulus development and function [PDF]
EMBO Journal, 2006 To advance our understanding of development, function and diseases in the kidney glomerulus, we have established and large-scale sequenced cDNA libraries from mouse glomeruli at different stages of development, resulting in a catalogue of 6053 different ...
Minoru Takemoto +2 more
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Ultrasmall polymeric nanocarriers for drug delivery to podocytes in kidney glomerulus [PDF]
Journal of Controlled Release, 2017 We explored the use of new drug-loaded nanocarriers and their targeted delivery to the kidney glomerulus and in particular to podocytes, in order to overcome the failure of current therapeutic regimens in patients with proteinuric (i.e.
Piergiorgio Messa +2 more
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Cell Biology of Kidney Glomerulus
1996It has been accepted that some artifacts are inevitably produced by the conventional preparation steps for electron microscopy, including fixation, dehydration, embedding, ultrathin sectioning, and staining. Therefore, conventional ultrastructural findings on kidney glomeruli are hardly thought to be correlated with the physiological functions of ...
S, Ohno +4 more
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Guarding the glomerulus: Diabetes and the kidney
Independent Nurse, 2020Beverley Bostock explains how missing a routine kidney test could harm diabetes ...
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Kidney Glomerulus Observation in Interactive VR Space
International Journal of Image and Graphics, 2003This paper presents the system designed to observe kidney glomeruli interactively with conventional CCD cameras and immersive virtual reality (VR) space. First, we captured the X-ray transmitted images and converted them to computer tomogram (CT). Second, the three-dimensional (3D) image was reconstructed using various image processing, binarization ...
Osamu Oshiro +6 more
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Recognition of kidney glomerulus by dynamic programming matching method
IEEE Transactions on Pattern Analysis and Machine Intelligence, 1988Dynamic programming was applied to locate the glomeruli in microscopic images of kidney tissue section. The glomeruli were modeled by a polygon whose sides could be varied within a given range of lengths. The objects were located by determining the best match of the model according to a so-called optimum criterion in which all possible shapes were ...
Hiromitsu Yamada +2 more
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Angiotensin II and the glomerulus: Focus on diabetic kidney disease
Current Hypertension Reports, 2003The renin-angiotensin system plays a key role in the progression of kidney disease, in addition to its well-described role in the maintenance of extracellular fluid volume and blood pressure. Recent studies have shown that blockade of the renin-angiotensin system at the level of the angiotensin II type 1 receptor can have important effects on ...
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