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Nephrological perspectives on the underutilization of SGLT2is in heart failure and chronic kidney disease

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı   +4 more
wiley   +1 more source
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Cell biology of kidney glomerulus.

International Review of Cytology, 1996
It has been accepted that some artifacts are inevitably produced by the conventional preparation steps for electron microscopy, including fixation, dehydration, embedding, ultrathin sectioning, and staining. Therefore, conventional ultrastructural findings on kidney glomeruli are hardly thought to be correlated with the physiological functions of ...
Shinichi Ohno   +4 more
semanticscholar   +3 more sources

Human kidney glomerulus proteome and biomarker discovery of kidney diseases

PROTEOMICS – Clinical Applications, 2008
AbstractThe kidney glomerulus is the site of plasma filtration and production of primary urine in the kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but also is the locus of kidney diseases progressing to chronic renal failure.
Y. Yoshida   +7 more
semanticscholar   +3 more sources

Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus.

Biochemical and Biophysical Research Communications, 2009
Thyroglobulin (Tg) is an essential substrate for thyroid hormone biosynthesis whose production is primarily limited to the thyroid follicular cell. We have previously identified an approximately 1.2 kb fragment of Tg mRNA in cultured mouse mesangial cells, and in the present study provide evidence showing that this transcript is transcribed and ...
Huhehasi Wu   +14 more
semanticscholar   +3 more sources

Recognition of Kidney Glomerulus by Dynamic Programming Matching Method

IEEE Transactions on Pattern Analysis and Machine Intelligence, 1988
Dynamic programming was applied to locate the glomeruli in microscopic images of kidney tissue section. The glomeruli were modeled by a polygon whose sides could be varied within a given range of lengths. The objects were located by determining the best match of the model according to a so-called optimum criterion in which all possible shapes were ...
Hiromitsu Yamada, C. Merritt, T. Kasvand
semanticscholar   +2 more sources

Isogenic Kidney Glomerulus Chip Engineered from Human Induced Pluripotent Stem Cells.

Journal of Visualized Experiments, 2022
Chronic kidney disease (CKD) affects 15% of the U.S. adult population, but the establishment of targeted therapies has been limited by the lack of functional models that can accurately predict human biological responses and nephrotoxicity.
Yasmin Roye, S. Musah
semanticscholar   +1 more source

Models of kidney glomerulus derived from human-induced pluripotent stem cells

iPSCs in Tissue Engineering, 2021
Human pluripotent stem cells hold tremendous promise for understanding tissue development and disease mechanisms, and for in vitro modeling of organ function.
Arinze E Okafor   +2 more
semanticscholar   +1 more source

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