Results 41 to 50 of about 897,477 (253)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Paired and altruistic kidney donation in the UK: algorithms and experimentation [PDF]
, 2012 We study the computational problem of identifying optimal sets of kidney exchanges in the UK. We show how to expand an integer programming-based formulation [1, 19] in order to model the criteria that constitute the UK definition of optimality.
David F. Manlove +3 more
core +1 more source
Neoplasia in horseshoe kidney with pyelic fusion and crossed single ureter
International Brazilian Journal of Urology, 2004 Horseshoe kidney with pyelic fusion and crossed single ureter is a rare anomaly, with only 3 cases described in the literature. Such anomaly can be accompanied by other abnormalities, such as congenital scoliosis and situs inversus totalis.
Renato P. Costa +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
P53 mutations in human adrenocortical neoplasms [PDF]
, 1994 The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Travis, W. +6 more
core +1 more source
International Brazilian Journal of Urology, 2004 INTRODUCTION: Liposarcoma is a malignant mesenchymal tumor frequently located in retroperitoneum, and rarely presenting an isolated lesion in kidney. CASE REPORT: Female, Caucasian, 49-year old patient, with family history of renal polycystic disease ...
Diogo A.L. Bader +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2014 The RIFLE (risk, injury, failure, loss, and end-stage) classification is widely used to gauge the severity of acute kidney injury, but its efficacy has not been formally tested in geriatric patients.
Chao, Chia-Ter;Wu, Vin-Cent;Lai, Chun-Fu;Shiao, Chih-Chung;Huang, Tao-Min;Wu, Pei-Chen;Tsai, I-Jung;Hou, Chun-Cheng;Wang, Wei-Jie;Tsai, Hung-Bin;Lin, Yu-Feng;Chiang, Wen-Chih;Lin, Shuei-Liong;Tsai, Pi-Ru;Ko, Wen-Je;Wu, Ming-Shiou;Wu, Kuan-Dun +1 more
core +1 more source
Late Malignant Oral Lesions after Kidney Transplantation
Brazilian Journal of Transplantation, 2023 Objective: To review cases of oral cavity malignancies available in the literature in kidney transplant recipients. Methods: A search was carried out in the PubMed database using the terms “oral cancer,” “mouth neoplasms,” “renal transplantation,” and ...
Paulo Sérgio da Silva Santos +2 more
doaj