Results 51 to 60 of about 1,445,514 (373)

Risk of critical illness among patients with solid cancers: a population-based observational study of 118,541 adults [PDF]

open access: yes, 2015
Importance: Critical illness may be a potential determinant of cancer outcomes and geographic variations, but its role has not been described before. Objective: To determine the incidence of admission to intensive care units (ICUs) within 2 years ...
Kinsella, John   +5 more
core   +1 more source

Neoplasia in horseshoe kidney with pyelic fusion and crossed single ureter

open access: yesInternational Brazilian Journal of Urology, 2004
Horseshoe kidney with pyelic fusion and crossed single ureter is a rare anomaly, with only 3 cases described in the literature. Such anomaly can be accompanied by other abnormalities, such as congenital scoliosis and situs inversus totalis.
Renato P. Costa   +2 more
doaj   +1 more source

The role of frailty in geriatric cranial neurosurgery for primary central nervous system neoplasms.

open access: yesNeurosurgical Focus, 2020
OBJECTIVE Frailty is a clinical state of increased vulnerability due to age-associated decline and has been well established as a perioperative risk factor. Geriatric patients have a higher risk of frailty, higher incidence of brain cancer, and increased
S. Shahrestani   +8 more
semanticscholar   +1 more source

Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta) [PDF]

open access: yes, 2017
Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands.
De Los Monteros, A E   +5 more
core   +1 more source

Clinical outcomes of IDH2‐mutated advanced‐phase Ph‐negative myeloproliferative neoplasms treated with enasidenib

open access: yesBritish Journal of Haematology, 2020
ance and cellular accumulation. Clin Pharmacol Ther. 2006;80:307–18. 4. Drawz P, Ayyappan S, Nouraie M, Saraf S, Gordeuk V, Hostetter T, et al. Kidney disease among patients with sickle cell disease, hemoglobin SS and SC. Clin J Am Soc Nephrol.
A. Patel   +11 more
semanticscholar   +1 more source

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

open access: yes, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA   +8 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The causal effect of serum micronutrients on malignant kidney neoplasm in European descent

open access: yesFrontiers in Oncology, 2023
PurposeObservational studies have revealed that serum minerals and vitamins are associated with cancer. However, the causal relationships between serum minerals and vitamins and renal malignancies remain unclear.MethodsMendelian randomization (MR) was ...
Pengfei Qiao   +3 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy