Results 171 to 180 of about 1,664,785 (304)

ZJU index and the prevalence of kidney stones in US adults: evidence from NHANES 2007-2018. [PDF]

BMC Urol
Zhong S, Li G, Tian C, Ding T, Jiang M, Diao P, Gan L, Ning L.   +7 more
europepmc   +1 more source

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Optimization of protein extraction and digestion workflows for proteomic analysis of saliva, salivary stones and kidney stones. [PDF]

Front Mol Biosci
Musiał N, Iwaniec M, Mruk I, Puchalski M, Tretiakow D, Skorek A, Szydłowski K, Szlęzak J, Czaplewska P.   +8 more
europepmc   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Intercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones. [PDF]

Proc Natl Acad Sci U S A
Schmidt WC, Mousavi A, Li J, Yang R, Gonzalez Marin G, Schreiber HL, Hammann RES, Obernuefemann CLP, Bergeron K, Klim A, Wong D, Du K, Hultgren SJ, Chen Q, Celestian A, Wong GCL, Scotland KB.   +16 more
europepmc   +1 more source

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small‐Cell Lung Cancer Models

Cancer Science, EarlyView.
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Kyoji Tsurumi, Miyuki Nomura, Mai Ouchi, Shigehiro Yagishita, Naohiko Kikuchi, Taku Sato, Mami Morita, Yoji Yamashita, Kayoko Hayashi, Tomoyoshi Soga, Akinobu Hamada, Tatsuro Fukuhara, Nobuhiro Tanuma   +12 more
wiley   +1 more source

Association between dietary and circulating folate markers and kidney stones in American adults: A cross-sectional NHANES analysis. [PDF]

Medicine (Baltimore)
Safargar M, Basiri A, Kord-Varkaneh H.
europepmc   +1 more source

A revised classification system of the marronoid clade of spiders (Araneae), based on dense sampling phylogenomics and comparative morphology

Cladistics, EarlyView.
Abstract The marronoid clade is a globally distributed, ecologically diverse group of spiders. It is an important faunal component in both natural and synanthropic environments, and even found in aquatic and extreme habitats such as desert salt flats. The systematics of the marronoid clade has been notoriously unstable due to the widespread character ...
Jonas O. Wolff, Michael B. J. Kelly, Franklyn Cala‐Riquelme, Jacob A. Gorneau, Katherine O. Montana, Helen M. Smith, Phil J. Sirvid, Cor J. Vink, Lauren A. Esposito, Martín J. Ramírez, Charles E. Griswold   +10 more
wiley   +1 more source

Association between skeletal muscle index and kidney stones in health screening populations: a single-center cross-sectional study. [PDF]

Transl Androl Urol
Huang L, Hu J, Cai X, Li H, Pan X, Zhang J, Chen T, Chen L.   +7 more
europepmc   +1 more source

How is the human microbiome linked to kidney stones? [PDF]

Front Cell Infect Microbiol
Pei X, Liu M, Yu S.
europepmc   +1 more source