Results 171 to 180 of about 49,486 (262)

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small‐Cell Lung Cancer Models

open access: yesCancer Science, EarlyView.
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Kyoji Tsurumi   +12 more
wiley   +1 more source

A revised classification system of the marronoid clade of spiders (Araneae), based on dense sampling phylogenomics and comparative morphology

open access: yesCladistics, EarlyView.
Abstract The marronoid clade is a globally distributed, ecologically diverse group of spiders. It is an important faunal component in both natural and synanthropic environments, and even found in aquatic and extreme habitats such as desert salt flats. The systematics of the marronoid clade has been notoriously unstable due to the widespread character ...
Jonas O. Wolff   +10 more
wiley   +1 more source

Histopathologic Characterization of Cutaneous Oxalosis Mimicking Calciphylaxis: Diagnostic Pitfalls and Polarized Light Evaluation

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Cutaneous oxalosis is an uncommon manifestation of primary hyperoxalosis, which can often resemble other cutaneous manifestations of end stage renal disease (ESRD), particularly calciphylaxis. We report the case of a 46 year old female with primary hyperoxaluria type one (PH1) believed to be well‐controlled on lumasiran, a small interfering ...
Shrina Patel   +3 more
wiley   +1 more source

ZJU index and the prevalence of kidney stones in US adults: evidence from NHANES 2007-2018. [PDF]

open access: yesBMC Urol
Zhong S   +7 more
europepmc   +1 more source

Implementing a behavioural intervention for paediatric type 1 diabetes: Key informant perspectives of multilevel barriers and facilitators

open access: yesDiabetic Medicine, EarlyView.
Providers, healthcare leaders, adolescents and caregivers identified evidence of intervention effectiveness in lowering glycaemic levels as a key facilitator of implementing a type 1 diabetes behavioural intervention. Critical barriers to implementation include buy‐in among clinic leaders, resource availability within clinics and meeting families ...
Julia Price   +6 more
wiley   +1 more source

Intercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones. [PDF]

open access: yesProc Natl Acad Sci U S A
Schmidt WC   +16 more
europepmc   +1 more source

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