Results 51 to 60 of about 273,215 (316)

Imlifidase in kidney transplantation

Clinical Kidney Journal
ABSTRACT Kidney transplantation, the gold-standard therapeutic approach for patients with end-stage kidney disease, offers improvement in patient survival and quality of life. However, broad sensitization against human leukocyte antigens often resulting in a positive crossmatch against the patient's living donor or the majority of ...
Kanbay, Mehmet, Copur, Sidar, Guldan, Mustafa, Topcu, Ahmet U., Ozbek, Lasin, Hasbal, Baris, Susal, Caner, Kocak, Burak, Callemeyn, Jasper, Segelmark, Marten   +9 more
openaire   +4 more sources

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Hemophagocytic lymphohistiocytosis secondary to virus infection and followed by lupus nephritis recurrence in a renal transplantation pediatric recipient: a case report

BMC Nephrology, 2023
Background Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening disorder characterized by systemic inflammation and organ failure as a result of dysregulated immune cell activation.
Jiyuan Li, Chen Gao, Xuejing Zhu, Danyi Yang, Wendan Mao, Hengchang Yao, Mingyang Deng, Liang Tan, Helong Dai, Xubiao Xie, Longkai Peng, Fenghua Peng   +11 more
doaj   +1 more source

Kidney Transplantation in Children

New England Journal of Medicine, 2014
This review discusses unique aspects of kidney transplantation in children that necessitate specialized approaches and have resulted in clinical advances so that kidney transplantations in young children have higher success rates than in any other age group.
V. R. Dharnidharka, P. Fiorina, W. E. Harmon   +2 more
openaire   +4 more sources

Kidney Transplantation 2: Care of the Kidney Transplant Recipient

DeckerMed Nephrology, Dialysis, and Transplantation, 2021
Renal transplantation is the preferred therapy for patients with end-stage kidney disease, leading to increased life expectancy, improved quality of life, and reduced health care resource use. Owing to their preexisting burden of disease, caring for renal transplant recipients is complex.
Belinda Lee, Martina M. McGrath, Jamil Azzi, Anil Chandraker   +3 more
openaire   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

Laparoscopic Kidney Transplantation

European Urology, 2010
We present the details of the first laparoscopic transplantation of a kidney from a living, related donor, performed April 16, 2009. Surgical and functional results were acceptable. Surgical time was 240 min (53 min for vascular suture), with blood loss of 300 cm(3) and a hospital stay of 14 d. Serum creatinine at discharge was 73 mmol/l.
Luis Guirado, S. Esquena, Guillermo Urdaneta, M. Montlleó, José Salvador, Antonio Rosales, J. Caffaratti, Humberto Villavicencio, Javier Ponce de León, Dyler Patiño   +9 more
openaire   +4 more sources

Perspectives of Older Kidney Transplant Recipients on Kidney Transplantation [PDF]

Clinical Journal of the American Society of Nephrology, 2017
Background and objectives Older kidney transplant recipients are susceptible to cognitive impairment, frailty, comorbidities, immunosuppression-related complications, and chronic graft failure, however, there has been limited focus on their concerns and expectations related to transplantation.
Jeremy R. Chapman, Germaine Wong, Germaine Wong, Germaine Wong, Allison Tong, Allison Tong, Camilla S. Hanson, Camilla S. Hanson, Jane O. Schell, Jule Pinter, Jule Pinter, Jule Pinter, Jonathan C. Craig, Jonathan C. Craig   +13 more
openaire   +3 more sources

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study

BMC Urology, 2020
Background For patients over the age of 70 years, sacral neuromodulation (SNM) is often not considered a potential therapeutic option. We therefore report on our results from performing SNM in elderly patients ≥70 years.
Sandra Schönburg, Tobias Bukethal, Paolo Fornara   +2 more
doaj   +1 more source