Results 51 to 60 of about 2,281,812 (411)

Correlation of serum soluble Klotho with fibroblast growth factor 23 levels in chronic kidney disease patients; a single centre study [PDF]

Journal of Nephropharmacology, 2020
Introduction: Klotho is a single-pass transmembrane protein with a long extracellular domain and short cytoplasmic tail that appears to modulate aging. Objectives: This cross-sectional investigation was conducted at a tertiary care centre to find the
Yuvaraj Anand, Vijayan Madhusudan, Parthasarathy Rajeevalochana, Mathew Milly, George Deepu, Abraham Georgi   +5 more
doaj   +1 more source

A Clinical Prediction Score to Guide Referral of Elderly Dialysis Patients for Kidney Transplant Evaluation. [PDF]

, 2017
IntroductionDialysis patients aged ≥70 years derive improved life expectancy through kidney transplantation compared to their waitlisted counterparts, but guidelines are not clear about how to identify appropriate transplantation candidates. We developed
Campbell, Kellie Hunter, Chen, Ling-Xin, Hedeker, Donald, Josephson, Michelle A, Saunders, Milda R, Stankus, Nicole   +5 more
core   +2 more sources

Belatacept and Long-Term Outcomes in Kidney Transplantation.

New England Journal of Medicine, 2016
BACKGROUND In previous analyses of BENEFIT, a phase 3 study, belatacept-based immunosuppression, as compared with cyclosporine-based immunosuppression, was associated with similar patient and graft survival and significantly improved renal function in ...
F. Vincenti, L. Rostaing, J. Grinyo, K. Rice, S. Steinberg, L. Gaite, M. Moal, G. Mondragón-Ramírez, J. Kothari, M. Polinsky, H. Meier‐Kriesche, S. Munier, C. Larsen   +12 more
semanticscholar   +1 more source

Assessment of hypertension-mediated organ damage in children and adolescents with hypertension

Blood Pressure, 2023
Purpose: Arterial hypertension (HT) is a main, potentially reversible cardiovascular risk factor. Long lasting HT leads to hypertension mediated organ damage (HMOD) of heart, vascular bed, and kidneys.
Michał Pac, Łukasz Obrycki, Jan Koziej, Krzysztof Skoczyński, Anna Starnawska-Bojsza, Mieczysław Litwin   +5 more
doaj   +1 more source

Elevated Circulating IL-10 Producing Breg, but Not Regulatory B Cell Levels, Restrain Antibody-Mediated Rejection After Kidney Transplantation

Frontiers in Immunology, 2021
BackgroundAntibody-mediated rejection (AMR) occupies a major position for chronic rejection after kidney transplantation. Regulatory B cell (Breg) has been reported to have an inhibitory immune function, which contributes to the resistance for AMR ...
Yongsheng Luo, Feifei Luo, Feifei Luo, Kuanxin Zhang, Shilei Wang, Haojie Zhang, Xianlei Yang, Wenjun Shang, Junxiang Wang, Zhigang Wang, Xinlu Pang, Yonghua Feng, Lei Liu, Hongchang Xie, Guiwen Feng, Jinfeng Li   +15 more
doaj   +1 more source

Alemtuzumab induction and tacrolimus monotherapy in pancreas transplantation: One- and two-year outcomes [PDF]

, 2006
BACKGROUND. Alemtuzumab (Campath-1H) induction with tacrolimus monotherapy has been shown to provide effective immunosuppression for kidney, liver, lung, and small bowel transplantation.
Abu-Elmagd, Akhtar Khan, Amadeo Marcos, Amit Basu, Calne, Ciano, Deanna Blisard, Flechner, Gruessner, Hale, Henkie P. Tan, John J. Fung, Kaufmann, Kirk, Knechtle, Knechtle, Kusum Tom, Marcos, Marcos, McCurry, Ngoc L. Thai, Ron Shapiro, Shapiro, Shapiro, Starzl, Starzl, Starzl, Starzl, Stuart, Thai, Thomas E. Starzl, Tryphonopoulos, Tzakis, Watson   +33 more
core   +1 more source

Mortality and Kidney Transplantation Outcomes Among Hepatitis C Virus-Seropositive Maintenance Dialysis Patients: A Retrospective Cohort Study.

American Journal of Kidney Diseases, 2019
RATIONALE & OBJECTIVE Hepatitis C virus (HCV) infection is common among maintenance dialysis patients. Few studies have examined both dialysis survival and transplantation outcomes for HCV-seropositive patients because registry data sets lack information
D. Sawinski, K. Forde, V. Lo Re, D. Goldberg, Jordana B. Cohen, J. Locke, R. Bloom, C. Brensinger, J. Weldon, J. Shults, P. Reese   +10 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Clinical outcomes of simultaneous pancreas-kidney transplantation in elderly type II diabetic recipients

Diabetology & Metabolic Syndrome
The effect of age on outcomes after simultaneous pancreas-kidney transplantation (SPK) among type II diabetes (T2DM) recipients remains inconclusive. This study aimed to analyze the relationship between the age at time of transplantation and mortality ...
Yu Cao, Jie Zhao, Gang Feng, Zhen Wang, Jianghao Wei, Yang Xu, Chunbai Mo, Wenli Song   +7 more
doaj   +1 more source

Kidney transplantation. Modern trends in kidney transplantation. [PDF]

, 1977
Trends in renal transplantation stem from recognition of the virtues and drawbacks of this kind of treatment and from a better appreciation of the interrelationship between transplantation and ...
Putnam, CW, Starzl, TE, Weil, R
core