Results 161 to 170 of about 45,578 (261)

Biomarkers for Early Detection of Diabetic Kidney Disease in Pediatric and Adolescent Populations: A Narrative Review. [PDF]

Health Sci Rep
Malekzadeh I, Falsafi N, Nazemi M, Taherkhani H, Bahroudi M, Abbas A, Moghtaderi M.   +6 more
europepmc   +1 more source

Network Pharmacology Combined With Metabonomics and Transcriptomics Reveals the Mechanism of Rubus Chingii Hu in Alleviating Nephrotoxicity Caused by Tripterygium Glycosides Tablet

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Flow chart of RCH to improve TGT‐induced nephrotoxicity. ABSTRACT Researches on Tripterygium glycosides tablets (TGT) often overlook renal toxicity from prolonged use. Rubus chingii Hu (RCH) is beneficial to kidney health and has an unclear role in reducing nephrotoxicity.
Cong Zhang, Zepeng Zhang, Tong Zhou, Lei Zhang   +3 more
wiley   +1 more source

Progression of diabetic nephropathy and adverse renal outcomes: possible involvement of Toll-like receptor 4 expression. [PDF]

Clin Exp Nephrol
Saito A, Abe F, Saito M, Hashimoto M, Kanazawa T, Kumagai T, Sakaguchi M, Ishii F, Nakayama T, Wakui H, Takahashi N.   +10 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2599-2622, August 2026.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Kidney tissue characterization using normalized raman imaging and segment-anything. [PDF]

Sci Rep
Karmakar R, Trim WV, Kirschner MW, Nørrelykke SF.   +3 more
europepmc   +1 more source

Nano‐Rosmarinic Acid Protects Against Chlorfenapyr‐Induced Testicular Toxicity Through Modulation of NRF2/HO‐1 and NF‐κB/NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Chlorfenapyr reduces testicular weight, sperm quality, and reproductive hormones. This study highlights that RA within chitosan nanoparticles (RA‐CHNPs) are superior to Rosmarinic acid in mitigating CFP‐induced testicular damage. RA within chitosan nanoparticles leads to the reduction of NF‐κB and NLRP3 expression in seminiferous tubules and activates ...
Ahmad Najem Alshammari, Ayat B. Al‐Ghafari, Huda A. Al Doghaither, Ahmed M. S. Hegazy, Ekramy M. Elmorsy, Asmaa Fady Sharif, Zahraa Khalifa Sobh   +6 more
wiley   +1 more source

Light chain deposition disease masquerading as hypophosphatemic osteomalacia: a case report. [PDF]

Front Med (Lausanne)
Chen J, Bing Q, Liu M, Zhao S, Wang Q, Hu Q, Zhao Z.   +6 more
europepmc   +1 more source

Isobavachin Attenuates Renal and Cardiac Injury in Chronic Hyperuricemia via Modulation of NF‐κB and NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Isobavachin alleviates HUA‐induced oxidative stress, inflammation, and fibrosis in the kidney and heart, potentially through its dual role in promoting UA excretion and inhibiting NF‐κB signaling and NLRP3 inflammasome activation. ABSTRACT Hyperuricaemia (HUA) is a recognized risk factor for cardiovascular and renal diseases.
Yongmei Li, Yuexin Xu, Wenjie Ye, Zeqi Yu, Zhenkun Wu, Xinyi Liu, Xuhong Huang, Jianxin Pang, Zean Zhao, Ting Wu   +9 more
wiley   +1 more source

Drug-induced hyperuricemia: multi-pathway regulation, causative drugs, and individualized management strategies. [PDF]

Front Pharmacol
Xiong B, Duan C, Xu S, Xu S, Yang C, He D, Luo C.   +6 more
europepmc   +1 more source

The Renal Function of the Wild Rodent Cerradomys goytaca Reveals Adaptations in the Mechanisms of Urinary Concentration and Solute Excretion

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 772-784, August 2026.
Renal adaptations of Cerradomys goytaca associated with survival in its natural habitat. Graphical Abstract of the main renal physiological characteristics identified in C. goytaca. This species exhibits an increased kidney mass index, elevated urine osmolality, and enhanced tubular water reabsorption, indicating a higher capacity for water ...
Luzia Agusta Valeriano‐Monici, Carolina de Augusta Barros Silva, Gustavo de Castro Nascimento, Lana Soares Sales, Carlos de Alberto Souza Filho, Edgar Mendes Souza Wan Der Maas Rosa, Patrick Gabriel Alencar dos Santos, Eulogio de Carlos Queiroz Carvalho, Jones Bernardes Graceli, Pablo Rodrigues Gonçalves, Jackson de Souza‐Menezes   +10 more
wiley   +1 more source