Results 71 to 80 of about 85,860 (310)

Changes in renal WT-1 expression preceding hypertension development [PDF]

, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica, Calvo, Juan Pablo, Casarotto, Mariana, Cuello Carrión, Fernando Darío, Ferder, León, Fornes, Miguel Walter, García, Isabel Mercedes, Manucha, Walter Ariel Fernando, Mazzei, Luciana Jorgelina   +8 more
core   +2 more sources

Morfometría de cortes histológicos de los túbulos renales normales en una muestra de humanos adultos

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Fundamento: los túbulos renales normales se han descrito por morfometría, lo que permite “reconstruir” en tercera dimensión la forma y el tamaño del espécimen estudiado.Objetivo: caracterizar la magnitud de los túbulos renales normales en humanos adultos,
Miosotis de Lourdes Fernández Lastre, Iraldo Mederos Pérez, Yardelys Rego Juhe, Sandor Varela Iraola, Tamara Caraballoso Recio   +4 more
doaj  

Research progress on the mechanism of kidney proximal tubule NHE3 in the angiotensin Ⅱ-dependent hypertension

Guangxi Yike Daxue xuebao
Hypertension is a multifactorial disorder involving genetic susceptibility, neuroendocrine dysregulation, cardiovascular and kidney dysfunction, and dietary factors.
LI Xiaochun, ZHUO Jialong, ZHENG Xiaowen, ZHAO Chunling, ZHANG Jianfeng, JIANG Yueming   +5 more
doaj   +1 more source

Elasticity, Shape Fluctuations and Phase Transitions in the New Tubule Phase of Anisotropic Tethered Membranes [PDF]

Phys.Rev.E57:1832-1863,1998, 1997
We study the shape, elasticity and fluctuations of the recently predicted (cond-mat/9510172) and subsequently observed (in numerical simulations) (cond-mat/9705059) tubule phase of anisotropic membranes, as well as the phase transitions into and out of it.
arxiv   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Theory of Cylindrical Tubules and Helical Ribbons of Chiral Lipid Membranes [PDF]

Phys. Rev. E 53, 3804 (1996), 1995
We present a general theory for the equilibrium structure of cylindrical tubules and helical ribbons of chiral lipid membranes. This theory is based on a continuum elastic free energy that permits variations in the direction of molecular tilt and in the curvature of the membrane.
arxiv   +1 more source

A technique to reduce fixation artifacts to kidney proximal tubules

Kidney International, 1984
The preservation of proximal tubules in a state most closely resembling their in vivo morphology requires careful attention to fixation procedures. Conventional excision-immersion fixation is known to result in swelling of the cells lining proximal tubules and the obliteration of proximal tubule lumens with microvilli and cellular debris [1–3 ...
Peter M. Andrews, Aline K. Coffey
openaire   +3 more sources

In Vivo Reprogramming of Tissue‐Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering

Advanced Science, EarlyView.
Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao, Shuyun Liu, Yizhuo Wang, Peng Lou, Ke Lv, Tian Wu, Lan Li, Qianyi Wu, Jiaying Zhu, Yanrong Lu, Meihua Wan, Jingping Liu   +11 more
wiley   +1 more source

Solvent drag measurement of transcellular and basolateral membrane NaCl reflection coefficient in kidney proximal tubule. [PDF]

, 1991
The NaCl reflection coefficient in proximal tubule has important implications for the mechanisms of near isosmotic volume reabsorption. A new fluorescence method was developed and applied to measure the transepithelial (sigma NaClTE) and basolateral ...
Fushimi, K, Shi, LB, Verkman, AS
core  

Segment-specific expression of 2P domain potassium channel genes in human nephron. [PDF]

, 2004
BackgroundThe 2P domain potassium (K2P) channels are a recently discovered ion channel superfamily. Structurally, K2P channels are distinguished by the presence of two pore forming loops within one channel subunit. Functionally, they are characterized by
Bockenhauer, Detlef, Goldstein, Steve AN, Levy, Daniel I, Velazquez, Heino   +3 more
core   +1 more source