Results 211 to 220 of about 620,224 (255)

FN3K deficiency drives tubular injury in diabetic kidney disease through impaired mitochondrial respiratory chain function. [PDF]

Front Endocrinol (Lausanne)
Cai D, Wu J, Yang X, He M.
europepmc   +1 more source

M1 macrophage‐derived exosomes aggravate diabetic nephropathy by regulating the WTAP/S1PR2 axis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Diabetic nephropathy (DN) is a severe microvascular complication of diabetes mellitus. The specific role of M1 macrophage‐derived exosomes in DN progression remains largely unexplored. Methods THP‐1 monocytes were differentiated into M0 macrophages and polarized into M1 macrophages for exosome extraction.
Lei Li, Hongmei Liu, Yu Mao, Huanhuan Wang, Lige Song, Zhiqiang Kang   +5 more
wiley   +1 more source

Microvascular autophagy and caspase-3 activation are central regulators of renal fibrosis after ischemia-reperfusion. [PDF]

JCI Insight
Kim H, Migneault F, Lan S, Kaci I, Turgeon J, Karakeussian Rimbaud A, Dupont M, Qi S, Dieudé M, Hébert MJ.   +9 more
europepmc   +1 more source

Metastatic mucinous tubular and spindle cell carcinoma of the kidney: Case report and literature review. [PDF]

SAGE Open Med Case Rep
Bokhari R, Al-Garni A, Bokhari HA.
europepmc   +1 more source

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan, Yumi Takiyama, Takao Takiyama, Yuri Takiyama, Hiroya Kitsunai, Hiroshi Nomoto   +5 more
wiley   +1 more source

INHAND: Non-proliferative and proliferative lesions of fish - Chapter 15. Fish urinary system. [PDF]

J Toxicol Pathol
Baumgartner W, Bach U, Baily J, Ruehl-Fehlert C, Fossey S, Furukawa S, Kato Y, Laast V, Meseck E, Schmidt-Posthaus H, Segner H, Shanmukhappa SK, Spitsbergen J, Wolf J.   +13 more
europepmc   +1 more source

Adaptation to extreme environments: A review of Antarctic fish physiology

Journal of Fish Biology, EarlyView.
Abstract Having evolved in the chronically cold and thermally stable waters of the Southern Ocean (SO) for millions of years, Antarctic fish possess a suite of physiological specializations that enable them to survive at temperatures near the freezing point of seawater. Adaptations include the evolution of antifreeze proteins, modifications of membrane
Seungyeon Lee, Sachithra Amarin Hettiarachchi, Il‐Chan Kim, Jae‐Seong Lee, Thomas Desvignes, Julia M. York, Laura Ghigliotti, Jilda Alicia Caccavo, Jin‐Hyoung Kim   +8 more
wiley   +1 more source

Early-life overconsumption of a high-carbohydrate diet induces metaflammation and kidney injury without impairment of function in adult Wistar rats. [PDF]

J Physiol Biochem
Sánchez-Solís CN, Hernández-Fragoso H, Diaz A, Vázquez-Roque R, Barbier OC, Avelino-Cruz JE, Treviño S.   +6 more
europepmc   +1 more source

Immunogenicity and Protective Efficacy of the First Autogenous Aeromonas hydrophila Vaccine for Piaractus brachypomus

Journal of Fish Diseases, EarlyView.
ABSTRACT Aeromonas hydrophila is a major zoonotic bacterial pathogen responsible for haemorrhagic septicemia, substantial economic losses in aquaculture and increasing antimicrobial resistance among field isolates. It is also one of the main bacterial species associated with mortality outbreaks in pirapitinga, Piaractus brachypomus, culture in the ...
Layana Aparecida Batista Pereira, Juliana do Nascimento Ferreira, Laine Patricia Costa dos Santos, Larissa Andréia Ferreira Sampaio, Igor Bartolomeu Alves de Barros, Elizabeth Gusmão Affonso, Jefferson Yunis‐Aguinaga, Gustavo da Silva Claudiano   +7 more
wiley   +1 more source

Spatiotemporal dynamics of renal distal convoluted tubule dilatation and cyst formation in nephronophthisis type 1 mice. [PDF]

Ren Fail
Zhang W, Xu G, Su X, Lai J, Xue Z, Li T, Huang H, Li R, Sun L, Li Y.   +9 more
europepmc   +1 more source