Results 231 to 240 of about 137,673 (303)

Mechanic evaluation of Jisheng Shenqi Wan on calcium oxalate kidney stones: an integrated network pharmacology and metabolomics. [PDF]

J Tradit Chin Med
Bing S, Yang LI, Zhuocheng J, Guozheng Q, Fan Z.   +4 more
europepmc   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Effect of Doum (<i>Hyphaene thebaica</i>) mesocarp and endosperm extracts on Triton X-100 induced hyperlipidemic rat: mitigative cardiovascular and renal dysfunction risks. [PDF]

Front Nutr
Almezail MS, Alhomaid RM.
europepmc   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

Altered ciliary morphology reduces mechanosensation in a cystic kidney model as indicated by a mathematical model. [PDF]

Sci Rep
Kumamoto K, Kagami H, Saitoh S, Yamada S, Matsumoto M, Ohno N.   +5 more
europepmc   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Galectin-3 in AKI: Pathogenic Target, Diagnostic Biomarker, or Both? [PDF]

Int J Biol Sci
Gui Y, Zhou D.
europepmc   +1 more source

Correction to "Neonatal Hyperoxia Downregulates Claudin-4, Occludin, and ZO-1 Expression in Rat Kidney Accompanied by Impaired Proximal Tubular Development". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

Combined antioxidant therapy with quercetin and curcumin protects against radiation-induced nephrotoxicity. [PDF]

Sci Rep
El-Hady AMA, Azzoz RM, Soliman SM, Khalil WM, Ali SA.   +4 more
europepmc   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source