Results 251 to 260 of about 137,673 (303)
Some of the next articles are maybe not open access.
Protein handling in kidney tubules
Nature Reviews NephrologyThe kidney proximal tubule reabsorbs and degrades filtered plasma proteins to reclaim valuable nutrients and maintain body homeostasis. Defects in this process result in proteinuria, one of the most frequently used biomarkers of kidney disease. Filtered proteins enter proximal tubules via receptor-mediated endocytosis and are processed within a highly ...
Andrew M Hall
openaire +5 more sources
Markers of Kidney Tubule Dysfunction and Major Adverse Kidney Events
Nephron, 2023<b><i>Background:</i></b> Serum creatinine and albuminuria are primary markers of glomerular function and injury, respectively. Tubular secretion, acid-base homeostasis, protein reabsorption, among other tubular functions, are largely ignored.
Alexander L, Bullen +5 more
openaire +2 more sources
C5aR Expression in Kidney Tubules, Macrophages and Fibrosis
Journal of Histotechnology, 2023The anaphylatoxin C5a and its receptor C5aR (CD88) are complement pathway effectors implicated in renal diseases, including ANCA-associated vasculitis. We investigated the kidney expression of C5aR and a second C5a receptor C5L2 by using immunohistochemistry and in situ hybridization on formalin-fixed, paraffin-embedded human and mouse kidney. C5aR was
Carolyn Dunlap +4 more
openaire +2 more sources
Electrolyte transport in kidney tubule cells
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1971Transtubular movement of Na and K takes place across an electrically negative cell compartment rich in K and poor in Na. Some properties of the luminal and peritubular cell boundaries with respect to ionic pump and leak characteristics are analysed. Sodium enters the tubule cell from the lumen down an electrochemical potential gradient.
G, Giebisch +2 more
openaire +2 more sources
Isolation of viable rat kidney tubules
Life Sciences, 1971Abstract A method has been devised for the isolation of viable tubules from the rat renal cortex. More than 70% of the preparation consisted of fragments of proximal tubules which respired in calcium- and glucose-free buffer solution. The addition of glucose or succinate to the medium enhanced the oxygen uptake and allowed for a linear respiration ...
H S, Ahn, H R, Strausser
openaire +2 more sources
Phenylalanine hydroxylation in isolated rat kidney tubules
International Journal of Biochemistry, 19901. Phenylalanine hydroxylation has been demonstrated to occur in isolated rat kidney tubules under physiological conditions. 2. The hydroxylation flux response is hyperbolic with apparent Km and Vmax values of ca 85 microM phenylalanine and 49 nmol tyrosine formed/mg dry wt per hr respectively. 3.
D, Askin +3 more
openaire +2 more sources
Primary Kidney Proximal Tubule Cells
2004Primary rabbit kidney epithelial cell cultures can be obtained that express renal proximal tubule functions. Toward these ends, renal proximal tubules are purified from the rabbit kidney by the method of Brendel and Meezan. To summarize, each kidney is perfused with iron oxide, which becomes associated with glomeruli.
openaire +2 more sources
Regenerating Tubules for Kidney Repair
2010Stem/progenitor cells are in the focus of regenerative medicine for a future therapy of acute and chronic renal failure. However, broad knowledge about parenchymal regeneration in kidney is lacking. For that reason developmental pathways leading from stem/progenitor cells to newly formed tubules have to be investigated.
W.W. Minuth, L. Denk, A. Roessger
openaire +1 more source
1958
Publisher Summary During the past few years kidney tubules have been submitted to several analyses with the aid of the electron microscope; analyses that provide information on the multitude of uncertainties associated with renal structures. The architecture of all the cells of the nephron is especially well adapted for the passage of fluid, a ...
openaire +1 more source
Publisher Summary During the past few years kidney tubules have been submitted to several analyses with the aid of the electron microscope; analyses that provide information on the multitude of uncertainties associated with renal structures. The architecture of all the cells of the nephron is especially well adapted for the passage of fluid, a ...
openaire +1 more source