Results 251 to 260 of about 139,844 (303)
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Electrolyte transport in kidney tubule cells
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1971Transtubular movement of Na and K takes place across an electrically negative cell compartment rich in K and poor in Na. Some properties of the luminal and peritubular cell boundaries with respect to ionic pump and leak characteristics are analysed. Sodium enters the tubule cell from the lumen down an electrochemical potential gradient.
G, Giebisch +2 more
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Isolation of viable rat kidney tubules
Life Sciences, 1971Abstract A method has been devised for the isolation of viable tubules from the rat renal cortex. More than 70% of the preparation consisted of fragments of proximal tubules which respired in calcium- and glucose-free buffer solution. The addition of glucose or succinate to the medium enhanced the oxygen uptake and allowed for a linear respiration ...
H S, Ahn, H R, Strausser
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Phenylalanine hydroxylation in isolated rat kidney tubules
International Journal of Biochemistry, 19901. Phenylalanine hydroxylation has been demonstrated to occur in isolated rat kidney tubules under physiological conditions. 2. The hydroxylation flux response is hyperbolic with apparent Km and Vmax values of ca 85 microM phenylalanine and 49 nmol tyrosine formed/mg dry wt per hr respectively. 3.
D, Askin +3 more
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Primary Kidney Proximal Tubule Cells
2004Primary rabbit kidney epithelial cell cultures can be obtained that express renal proximal tubule functions. Toward these ends, renal proximal tubules are purified from the rabbit kidney by the method of Brendel and Meezan. To summarize, each kidney is perfused with iron oxide, which becomes associated with glomeruli.
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Protein handling in kidney tubules
Nature Reviews NephrologyThe kidney proximal tubule reabsorbs and degrades filtered plasma proteins to reclaim valuable nutrients and maintain body homeostasis. Defects in this process result in proteinuria, one of the most frequently used biomarkers of kidney disease. Filtered proteins enter proximal tubules via receptor-mediated endocytosis and are processed within a highly ...
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Regenerating Tubules for Kidney Repair
2010Stem/progenitor cells are in the focus of regenerative medicine for a future therapy of acute and chronic renal failure. However, broad knowledge about parenchymal regeneration in kidney is lacking. For that reason developmental pathways leading from stem/progenitor cells to newly formed tubules have to be investigated.
W.W. Minuth, L. Denk, A. Roessger
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1958
Publisher Summary During the past few years kidney tubules have been submitted to several analyses with the aid of the electron microscope; analyses that provide information on the multitude of uncertainties associated with renal structures. The architecture of all the cells of the nephron is especially well adapted for the passage of fluid, a ...
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Publisher Summary During the past few years kidney tubules have been submitted to several analyses with the aid of the electron microscope; analyses that provide information on the multitude of uncertainties associated with renal structures. The architecture of all the cells of the nephron is especially well adapted for the passage of fluid, a ...
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Inhibition of kidney tubule induction by charged polymers
Cell Differentiation, 1978Charged polymers, known to alter cell surface characteristics, reversibly inhibit the intercellular communication required in kidney tubule induction. This effect seems to be a function of their charge density. It is suggested that this effect is due to the formation of a molecular barrier between the interacting cell surfaces.
P, Ekblom, S, Nordling, L, Saxén
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A Kallikrein-Specific Inhibitor in Rat Kidney Tubules
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1976A kallikrein inhibitor was found in tubules of the rat kidney and purified by chromatography on Sephadex G-100. The molecular weight of the inhibitor, estimated by gel filtration and dodecylsulfate electrophoresis, is about 4700. It inhibits the following kallikreins: porcine submanidbular and pancreatic kallikrein, rat kidney and urine kallikrein, and
R, Geiger, K, Mann
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[Tumorigenesis of kidney tubule].
Nihon rinsho. Japanese journal of clinical medicine, 1995Renal cell carcinoma is derived from renal tubule, blastematous tubule or nephrogenic rest. Most common sporadic clear cell tumors have structural changes of the chromosomes, such as the cancer suppressor genes at 3p14, 3p21 or 3p25 (VHL gene). Cytogenetically, clear cell tumor (non papillary tumor) initially develops as a cancer, while papillary tumor
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