Results 111 to 120 of about 1,582,096 (296)

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

A Novel Self-aligned and Maskless Process for Formation of Highly Uniform Arrays of Nanoholes and Nanopillars

Nanoscale Research Letters, 2008
Fabrication of a large area of periodic structures with deep sub-wavelength features is required in many applications such as solar cells, photonic crystals, and artificial kidneys.
Wu Wei, Dey Dibyendu, Memis Omer, Katsnelson Alex, Mohseni Hooman   +4 more
doaj   +1 more source

Artificial Intelligence Approaches to Medical Diagnosis [PDF]

, 1974
Work reported herein was conducted at the Artificial Intelligence Laboratory, a Massachusetts Institute of Technology research program supported in part by the Advanced Research Projects Agency of the Department of Defense and monitored by the Office of ...
Rubin, Andee
core  

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Assessing Change in Stone Burden on Baseline and Follow-Up CT: Radiologist and Radiomics Evaluations

Journal of Imaging
This retrospective diagnostic accuracy study compared radiologist-based qualitative assessments and radiomics-based analyses with an automated artificial intelligence (AI)–based volumetric approach for evaluating changes in kidney stone burden on follow ...
Parisa Kaviani, Matthias F. Froelich, Bernardo Bizzo, Andrew Primak, Giridhar Dasegowda, Emiliano Garza-Frias, Lina Karout, Anushree Burade, Seyedehelaheh Hosseini, Javier Eduardo Contreras Yametti, Keith Dreyer, Sanjay Saini, Mannudeep Kalra   +12 more
doaj   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Preoperative and postoperative imaging as a surgical strategy and feedback on abdominal aortic aneurysm with horseshoe kidney: Case report

SAGE Open Medical Case Reports
A 77-year-old man was diagnosed with an infrarenal abdominal aortic aneurysm coexisting with a horseshoe kidney detected on a computed tomography (CT) scan.
Shizuko Iwasa, Takeshi Katsube, Azumi Hamasaki   +2 more
doaj   +1 more source

Lactococcus garvieae as a Novel Pathogen in Cultured Pufferfish (Takifugu obscurus) in China

Fishes
In October 2023, a disease outbreak in pufferfish (Takifugu obscurus) farms in Zhongshan City, Guangdong, China, caused high mortality. Diseased fish (mean length: 15 ± 1 cm) exhibited swimming disorders, fin rot, hemorrhage, and an enlarged spleen ...
Ruilong Xu, Zhongning He, Yiyang Deng, Yihao Cen, Zequan Mo, Xueming Dan, Yanwei Li   +6 more
doaj   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

Harnessing Artificial Intelligence for Enhanced Renal Analysis: Automated Detection of Hydronephrosis and Precise Kidney Segmentation

European Urology Open Science
Background and objective: Hydronephrosis is essential in the diagnosis of renal colic. We automated the detection of hydronephrosis from ultrasound images to standardize the therapy and reduce the misdiagnosis of renal colic.
Radu Alexa, Jennifer Kranz, Rafael Kramann, Christoph Kuppe, Ritabrata Sanyal, Sikander Hayat, Luis Felipe Casas Murillo, Turkan Hajili, Marco Hoffmann, Matthias Saar   +9 more
doaj   +1 more source