Results 71 to 80 of about 35,864 (296)

Artificial intelligence for the artificial kidney: Pointers to the future of a personalized hemodialysis therapy [PDF]

, 2018
Current dialysis devices are not able to react when unexpected changes occur during dialysis treatment, or to learn about experience for therapy personalization.
Ramos, Rosa, Vellido Alcacena, Alfredo, Cruzado, Josep M, Nuria Montero, Josep Maria Cruzado, Miguel Hueso, Rosa Ramos, Manuel Angoso, Angoso, Manuel, Angoso de Guzmán, Manuel, Cruzado, Josep Ma., Montero, Nuria, Jonsson, Anders, 1973-, Alfredo Vellido, Anders Jonsson, Jonsson, Anders, Hueso Val, Miquel, Barbieri, Carlo, Carlo Barbieri, Hueso, Miguel   +19 more
core   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Oxidatively modified proteins in kidneys of rats fed with glyphosate-resistant genetically modified soybean and the herbicide Roundup

Regulatory Mechanisms in Biosystems, 2019
Genetic technologies have become a tool for achieving the desired properties of plant crops instead of traditional breeding in recent decades. They consist in artificial editing of a plant genome (genetic modification) by inserting the genes encoding ...
I. V. Chorna, G. B. Dronik, T. O. Lukashiv, V. D. Yuzkova   +3 more
doaj   +1 more source

Histological and physiological effects of Sustanon on the liver and Kidneys of male rats

, 2017
     This research on male rats was carried out to investigate the possible effects of three different doses of artificial testosterone (Sustanon) on the histology and function of liver and kidneys of adult male rats.
Hamza, Ekhlas Abd, Rashid, Kareem Hameed
core   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Nanotechnology in Urology

Indian Journal of Urology, 2017
Introduction: Nanotechnology has revolutionized our approach to medical diagnostics as well as therapeutics and has spanned an entirely new branch of research. This review addresses the potential applications of Nanotechnology in Urology. This article is
Sudhindra Jayasimha
doaj   +1 more source

Probing expert opinions on the future of kidney replacement therapies

, 2021
Patients with kidney failure can only survive with some form of kidney replacement(transplant or dialysis). Unfortunately, innovations in kidney replacement therapylag behind many other medical fields.
Fabio Batista Mota, Mota, Fabio Batista, Bonventre, Joseph V., Cabral, Bernardo Pereira, Wieringa, Fokko, Bernardo Pereira Cabral, Joseph V. Bonventre, Fokko Wieringa   +7 more
core   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Smart transplants: emerging role of nanotechnology and big data in kidney and islet transplantation, a frontier in precision medicine

Frontiers in Immunology
Kidney and islet transplantation has revolutionized the management of renal failure and diabetes. Transplantation is considered as excellent therapeutic intervention for most suitable patients.
Rajkiran Deshpande, Titus Augustine, Titus Augustine   +2 more
doaj   +1 more source