Results 71 to 80 of about 1,582,096 (296)

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li   +13 more
wiley   +1 more source

A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations

open access: yesRenal Replacement Therapy, 2019
The widening gap between organ availability and need is resulting in a worldwide crisis, particularly concerning kidney transplantation. Regenerative medicine options are becoming increasingly advanced and are taking advantage of progress in novel ...
Nicholas M. Wragg   +2 more
doaj   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li   +15 more
wiley   +1 more source

MOF-808/graphene oxide composite as an efficient adsorbent for urea removal: experimental and atomistic study

open access: yesScientific Reports
This study explores the synthesis and evaluation of a novel composite material based on the in-situ growth of Metal-Organic Framework (MOF) on graphene oxide composite for the removal of urea from aqueous environments, particularly for artificial kidney ...
Nahid Khandan   +2 more
doaj   +1 more source

Numerical study on hydromagnetic nanofluid convective flow through artificial kidney with the effects of hall currents past porous stretching cylinder

open access: yesPartial Differential Equations in Applied Mathematics
This work investigates how Hall currents influence the convection flow of a hydromagnetic nanofluid past a porous stretching cylinder through hollow tubes in an artificial kidney. Dialysis removes more metabolic excretory products and naturally occurring
Christopher Venance
doaj   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

open access: yesAdvanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang   +8 more
wiley   +1 more source

Sweet, bloody consumption – what we eat and how it affects vascular ageing, the BBB and kidney health in CKD

open access: yesGut Microbes
In today’s industrialized society food consumption has changed immensely toward heightened red meat intake and use of artificial sweeteners instead of grains and vegetables or sugar, respectively.
Angelina Schwarz   +7 more
doaj   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

open access: yesAdvanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi   +14 more
wiley   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

open access: yesAdvanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang   +8 more
wiley   +1 more source

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