Results 61 to 70 of about 2,965,710 (272)

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Killing Vector Fields on the Lorentzian Manifold of Non-Static Special Axially Symmetric Space-Time [PDF]

, 2015
In this work direct integration and algebraic techniques have been implied to study the Killing vector fields in special non-static axially symmetric space-time.
Ahmad, Israr, Ali, Amjad
core   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Ricci Solitons and Generalized Ricci Solitons Whose Potential Vector Fields Are Jacobi-Type

Journal of Mathematics
This paper is devoted to Ricci solitons admitting a Jacobi-type vector field. First, we present some rigidity results for Ricci solitons Mn,g,V,λ admitting a Jacobi-type vector field ξ and provide conditions under which ξ is Killing.
Vahid Pirhadi, Ghodratallah Fasihi-Ramandi, Shahroud Azami   +2 more
doaj   +1 more source

Riemann Solitons on a Spacetime with the Spatially Homogeneous Rotating Metric

Axioms
This manuscript presents a comprehensive taxonomy of Riemann solitons within the framework of a spacetime manifold endowed with a metric exhibiting both spatial homogeneity and rotational characteristics.
Majid Ali Choudhary, Foued Aloui, Ibrahim Al-Dayel   +2 more
doaj   +1 more source

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

Advanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang, Zhudong Liu, Yuqiao Yin, Jing Su, Dunyang Yu, Longsheng Xing, Zhen Zou, Le Kang, Jianghua Sun   +8 more
wiley   +1 more source

On a Relation Between Twistors and Killing Spinors

Cumhuriyet Science Journal, 2018
Inspiring from the consequence of constructingconformal Killing-Yano forms out of Killing-Yano forms and closed conformalKilling-Yano forms, this work includes a method for building up twistors fromKilling spinors which can be analogously interpreted as ...
Özgür Açık
doaj   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

On the structure vector field of a real hypersurface in complex quadric

Open Mathematics, 2018
From the notion of Jacobi type vector fields for a real hypersurface in complex quadric Qm we prove that if the structure vector field is of Jacobi type it is Killing when the real hypersurface is either Hopf or compact.
Dios Pérez Juan de
doaj   +1 more source

Killing vector fields on semi-Riemannian product manifolds [PDF]

, 2023
Hano's theorem states that the space of Killing vector fields of a complete simply connected Riemannian manifold is isomorphic to the direct sum of the Killing vector fields of the factors in its de Rham decomposition.
Costanza, Federico, Leistner, Thomas
core