Results 71 to 80 of about 822,225 (257)
KIM-1 expression in kidney allograft biopsies: Improving the gold standard [PDF]
Kidney International, 2008 Long-term outcomes of kidney allografts have shown only marginal improvement over the last three decades, despite the remarkable improvement in acute rejection and one-year graft survival. Novel biomarkers of tubular injury may prevent irreversible damage to the tubulointerstitial compartment and improve allograft survival.
openaire +2 more sources
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Кубанский научный медицинский вестникBackground. The COVID-19 pandemic has revealed previously overlooked clinical features of infectious and inflammatory kidney diseases in pediatric patients.
N. I. Axmedjanova +2 more
doaj +1 more source
Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree +9 more
wiley +1 more source
Frontiers in MedicineBackgroundKidney Injury Molecule 1 (KIM-1) is a biomarker of proximal tubular injury that can be used for the early detection of acute kidney injury (AKI).
Yun Su +6 more
doaj +1 more source
Kidney injury molecule-1 is involved in the apoptosis of renal tubular cell line HK-2 induced by iodine contrast [PDF]
Jichu yixue yu linchuang, 2020 Objective To explore the role and the possible mechanism of kidney injury molecule-1(KIM-1) in the contrast-induced apoptosis of renal tubular epithelial cell.
YU Rui, ZHANG Xin-ru, WANG Dan-dan, HE Ping, BAI Yu, TIAN Mi, ZHANG Bei-ru
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
KIM-1/TIM-1 in proximal tubular cell immune response
Oncotarget, 2015 Kidney injury molecule-1/T cell IgG and mucin containing 1 (KIM-1/TIM-1) is a type 1 membrane receptor [1] which we identified as the most upregulated proximal tubular cell (PTC) protein following a variety of kidney injuries in animal models and human diseases [1] (Figure (Figure1A).1A).
Craig R, Brooks, Joseph V, Bonventre
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Friedreich Ataxia (FRDA) is a neurodegenerative disorder of children and young adults associated with cardiomyopathy and other systemic complications. We report a 10‐year‐old girl who presented simultaneously with Acute Myelogenous Leukemia and FRDA who was successfully treated for her leukemia with allogeneic hematopoietic stem cell ...
Alexandra Gitman +5 more
wiley +1 more source
Circulating kidney injury molecule‐1 as a biomarker of renal parameters in diabetic kidney disease
Journal of Diabetes Investigation, 2020 Aims/Introduction Urinary kidney injury molecule‐1 (KIM‐1) has been associated with proximal tubular damage in human and animal studies. Although it has been recognized as a biomarker of acute kidney injury and chronic kidney disease, its significance in
Tomohito Gohda +10 more
doaj +1 more source