Results 201 to 210 of about 32,949 (273)

Deciphering the Counterintuitive Role of Vascular Endothelial Growth Factor Signaling Pathways in Pulmonary Arterial Hypertension. [PDF]

Int J Mol Sci
Scagliola R.
europepmc   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

A Nonviral Neo‐Nucleocapsid for Cell‐Specific RNA Delivery Developed by Pseudo‐Cyclic Peptide Grafting and Directed Evolution

Angewandte Chemie, EarlyView.
Nonviral neo‐nucleocapsids developed from a repurposed bacterial protein cage, and macrocyclic peptide pharmacophores via protein‐protein ligation, bacteria‐based directed evolution, lasso‐grafting, and mammalian cell‐based directed evolution enabled cell specific RNA delivery.
Daiki Kanayama, Naohiro Terasaka, Kazuki Kato, Sae Okazaki, Hiroaki Suga   +4 more
wiley   +2 more sources

Phosphorylation at S1288 of leukemia associated RhoGEF (LARG/ARHGEF12) induces plasma membrane localization and promotes binding and activation of RhoA. [PDF]

J Biol Chem
Yang WS, Ghanem NZ, Scahill SD, Caliva MJ, Röttig H, Fitz A, Matter ML, Ramos JW.   +7 more
europepmc   +1 more source

Assessing Angiogenic Properties In Vitro or In Ovo of Pre‐Crosslinked Alginate‐Dialdehyde‐Gelatin Hydrogels Incorporating Boron‐Doped Mesoporous Bioactive Glass Particles

Advanced NanoBiomed Research, EarlyView.
This study examines the influence of boron‐doped mesoporous bioactive glass nanoparticles (MBGN) blended in cast and 3D‐printed pre‐crosslinked alginate‐dialdehyde‐gelatin (ADA‐GEL). Addition of 0.5% and 1% MBGN did not negatively affect the viability of human umbilical vein endothelial cells (HUVECs), or the sprouting of HUVEC spheroids.
Rafael Schmid, Yvonne Kulicke, Evelin Sandor, Hsuan‐Heng Lu, Stefan Fleischer, Isabell Lang, Harald Wajant, Hana Kaňková, Andreas Arkudas, Annika Kengelbach‐Weigand, Raymund E. Horch, Aldo R. Boccaccini, Theresa Promny   +12 more
wiley   +1 more source

Collagen Signaling via DDR1 Exacerbates Barriers to Macromolecular Drug Delivery in a 3D Model of Pancreatic Cancer Fibrosis. [PDF]

Small
Ohira M, Kitamura M, Iwasaki H, Ohta-Okano H, Tsujii H, Nakamura R, Nakazawa T, Nishiguchi A, Yamamoto M, Osada K, Toyooka S, Cabral H, Masamune A, Kano MR, Tanaka HY.   +14 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Bending the boundaries: the many facets of endophilin-As from membrane dynamics to disease. [PDF]

Cell Mol Life Sci
Xu S, Rigaux E, Hène D, Renard HF, Thines L.   +4 more
europepmc   +1 more source

Impact of FLT3 mutation on its intracellular localization and implications for anti-leukemia strategy. [PDF]

Ann Hematol
Song F, Su L, Gao S.
europepmc   +1 more source

Targeting vascular endothelial growth receptor-2 (VEGFR-2): structural biology, functional insights, and therapeutic resistance. [PDF]

Arch Pharm Res
Shah FH, Nam YS, Bang JY, Hwang IS, Kim DH, Ki M, Lee HW.   +6 more
europepmc   +1 more source