Results 241 to 250 of about 32,949 (273)
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[Expression of kinase insert domain-containing receptor in prostate adenocarcinoma].
Zhonghua nan ke xue = National journal of andrology, 2007To investigate the correlation between the expression of the kinase insert domain-containing receptor (KDR) and the histological grade of prostate adenocarcinoma.Forty-eight samples of prostate adenocarcinoma tissues and 20 samples of benign prostatic hypertrophy (BPH) tissues were studied by LsAB immunohistochemical staining.The positive expression ...
An-sheng, Bai +5 more
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Fertility and Sterility, 2013
To investigate whether kinase insert domain-containing receptor (KDR) gene polymorphisms are risk factors for recurrent spontaneous abortion (RSA) in Korean women.Case-control study.University hospital.Three hundred twenty-seven idiopathic RSA patients and 230 controls with Korean ethnicity.None.The KDR -604T→C (rs2071559), 1192G→A (rs2305948), and ...
Hyungchul, Rah +6 more
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To investigate whether kinase insert domain-containing receptor (KDR) gene polymorphisms are risk factors for recurrent spontaneous abortion (RSA) in Korean women.Case-control study.University hospital.Three hundred twenty-seven idiopathic RSA patients and 230 controls with Korean ethnicity.None.The KDR -604T→C (rs2071559), 1192G→A (rs2305948), and ...
Hyungchul, Rah +6 more
openaire +2 more sources
Genes & Genomics, 2012 Kinase insert domain receptor (KDR) gene polymorphisms are associated with coronary artery lesions. The aims of this study were to evaluate the role of KDR polymorphisms in patients susceptible to cerebral white matter lesion (cWML), and determine the relationship between KDR polymorphisms and plasma total homocysteine levels.
Su Yeoun Kim +9 more
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Human Gene Therapy, 2000
The destruction of newly forming tumor vasculature is a promising approach to inhibit tumor growth. The goal of the present study was to investigate whether human lymphocytes gene modified to express a chimeric receptor specific for the angiogenic endothelial cell receptor, KDR, could react against KDR(+) cells.
M H, Kershaw +5 more
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The destruction of newly forming tumor vasculature is a promising approach to inhibit tumor growth. The goal of the present study was to investigate whether human lymphocytes gene modified to express a chimeric receptor specific for the angiogenic endothelial cell receptor, KDR, could react against KDR(+) cells.
M H, Kershaw +5 more
openaire +2 more sources
Medical Oncology, 2014
Kinase insert domain receptor (KDR) is the principal receptor that promotes the pro-angiogenic action of vascular endothelial growth factor and has been the principal target of anti-angiogenic therapies. Our aim was to determine whether single-nucleotide polymorphisms (SNPs) in KDR gene are associated with clinical outcomes after first-line sorafenib ...
You-Bing, Zheng +10 more
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Kinase insert domain receptor (KDR) is the principal receptor that promotes the pro-angiogenic action of vascular endothelial growth factor and has been the principal target of anti-angiogenic therapies. Our aim was to determine whether single-nucleotide polymorphisms (SNPs) in KDR gene are associated with clinical outcomes after first-line sorafenib ...
You-Bing, Zheng +10 more
openaire +2 more sources
Biochemistry, 1995
To investigate the effects of metal ion binding to the alpha-PDGFR kinase insert domain, a PCR product representing amino acid residues 691-795 (104 amino acids) was bacterially expressed and purified. Secondary structure prediction and circular dichroism spectroscopy indicated this domain to be a mixed alpha + beta protein with a large coil/turn ...
D, Mahadevan +8 more
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To investigate the effects of metal ion binding to the alpha-PDGFR kinase insert domain, a PCR product representing amino acid residues 691-795 (104 amino acids) was bacterially expressed and purified. Secondary structure prediction and circular dichroism spectroscopy indicated this domain to be a mixed alpha + beta protein with a large coil/turn ...
D, Mahadevan +8 more
openaire +2 more sources
Anticancer Research, 2015 Ovarian cancer is the second most common gynecological malignancy after cancer of the uterine corpus, and the fifth leading cause of cancer-related death among women. It has been discovered that cyclin I (CCNI) protein expression correlates with the proliferation of cancer cells and expression of angiogenesis-related proteins, such as vascular ...
Marek Cybulski +6 more
+5 more sources
Cancer research, 2001
Vascular endothelial growth factor (VEGF) binds to and mediates its activity mainly through two tyrosine kinase receptors, VEGF receptor 1 [or fms-like tyrosine kinase receptor (Flt-1)] and VEGF receptor 2 [or kinase insert domain-containing receptor (KDR)].
D, Lu +6 more
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Vascular endothelial growth factor (VEGF) binds to and mediates its activity mainly through two tyrosine kinase receptors, VEGF receptor 1 [or fms-like tyrosine kinase receptor (Flt-1)] and VEGF receptor 2 [or kinase insert domain-containing receptor (KDR)].
D, Lu +6 more
openaire +1 more source