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Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? [PDF]

open access: yesFront Cell Infect Microbiol
van der Mescht MA   +3 more
europepmc   +1 more source

TREM2 and sTREM2 in Alzheimer's disease: from mechanisms to therapies. [PDF]

open access: yesMol Neurodegener
Zhang L, Xiang X, Li Y, Bu G, Chen XF.
europepmc   +1 more source

LIM kinases in cardiovascular health and disease. [PDF]

open access: yesFront Physiol
Lateef OM   +5 more
europepmc   +1 more source
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Capture of flowing endothelial cells using surface-immobilized anti-kinase insert domain receptor antibody.

Tissue Engineering Part C: Methods, 2008
In humans, self-endothelialization of synthetic grafts is severely limited, but a recent interesting idea is to attract endothelial progenitor cells (EPCs) from peripheral blood onto grafts via antibodies directed at proposed EPC markers.
B. D. Markway   +5 more
semanticscholar   +4 more sources

The relationship of kinase insert domain receptor gene polymorphisms and clinical outcome in advanced hepatocellular carcinoma patients treated with sorafenib

Medical Oncology, 2014
Kinase insert domain receptor (KDR) is the principal receptor that promotes the pro-angiogenic action of vascular endothelial growth factor and has been the principal target of anti-angiogenic therapies. Our aim was to determine whether single-nucleotide polymorphisms (SNPs) in KDR gene are associated with clinical outcomes after first-line sorafenib ...
You-bing Zheng   +10 more
semanticscholar   +4 more sources

Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation

The FASEB Journal, 2014
Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development and homeostasis. VEGF receptor 2 (VEGFR-2) is the major receptor involved in vasculogenesis and angiogenesis and regulates endothelial cell survival, migration, and mitogenesis.
S. Manni   +4 more
semanticscholar   +4 more sources

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