Results 41 to 50 of about 2,014 (136)

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]

open access: yes, 2012
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
A Bosutti   +189 more
core   +2 more sources

Key targets for activating anaesthesia shared decision‐making: a mixed methods systematic review

open access: yesAnaesthesia, Volume 81, Issue 6, Page 852-866, June 2026.
Summary Introduction Shared decision‐making in anaesthesia is widely endorsed yet delivered inconsistently. This mixed methods systematic review aimed to identify primary activation targets for enhancing shared decision‐making in peri‐operative anaesthesia practice. Methods Databases were searched for qualitative, quantitative and mixed methods studies
Adam Madhani   +2 more
wiley   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng   +9 more
wiley   +1 more source

Insulin‐like growth factor 1 receptor correlates with verbal memory in ILAE type 2 hippocampal sclerosis

open access: yesEpilepsia, Volume 67, Issue 5, Page 2572-2584, May 2026.
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz   +10 more
wiley   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Atypical “seizure-like” activity in cortical reverberating networks in vitro can be caused by LPS-induced inflammation: a multi-electrode array study from a hundred neurons [PDF]

open access: yes, 2014
We show here that a mild sterile inflammation induced by the endotoxin lipopolysaccharide (LPS), in a neuron/astrocyte/microglial cortical network, modulates neuronal excitability and can initiate long-duration burst events resembling epileptiform ...
Alida Amadeo   +6 more
core   +5 more sources

Exploring Cognitive, Behavioral, and Psychological Dimensions in Persistent Idiopathic Facial Pain and Other Chronic Orofacial Pain Conditions

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
This case‐control study assessed 42 chronic orofacial pain patients, including 23 patients with persistent idiopathic facial pain, and 42 controls. COPc patients showed cognitive deficits, mood symptoms, alexithymia, and maladaptive coping, especially catastrophizing.
Alessandra Telesca   +8 more
wiley   +1 more source

Anticonvulsant Effects of Citronellal, Daidzin, and Phytol, Possibly Through GABAA Receptor and Voltage‐Gated Sodium Channel Interaction Pathways: In Vivo and In Silico Studies

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
Citronellal, daidzin, and phytol exert significant anticonvulsant effects in a chick seizure model by enhancing GABAergic transmission and blocking voltage‐gated sodium channels, with combination therapies showing enhanced efficacy and a favorable safety profile.
Emon Mia   +9 more
wiley   +1 more source

P2X receptors as targets for the treatment of status epilepticus. [PDF]

open access: yes, 2013
Prolonged seizures are amongst the most common neurological emergencies. Status epilepticus is a state of continuous seizures that is life-threatening and prompt termination of status epilepticus is critical to protect the brain from permanent damage ...
Diaz-Hernandez, Miguel   +3 more
core   +1 more source

Antiepileptic activity of hydroalcoholic extract of basil in mice [PDF]

open access: yes, 2014
Introduction: Epilepsy has been always considered as one of the most prevalent disorders of nervous system and despite various drugs available, there are still some patients who have drug resistance.
Asadi-Samani, Majid.   +2 more
core  

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