Results 21 to 30 of about 2,014 (136)

The Use of Carbamazepine (Tegretol) in Psychiatry and Its Association to Kindling, Temporal Lobe Epilepsy and Psychopathology [PDF]

, 2011
The recent theory of kindling may help to link neurophysiologic, neurotransmitter and neuroanatomic mechanisms important in understanding the neurology of behavior.
Stanch, M.D., James
core   +1 more source

Acute seizures in acute ischemic stroke: does thrombolysis have a role to play? [PDF]

, 2013
Seizures appear at stroke presentation, during the acute phase or as a late complication of stroke. Thrombolysis has not been investigated as a risk factor despite its potential neurotoxic effect.
Alvarez, V., Michel, P., Papavasileiou, V., Rossetti, A.O.   +3 more
core   +1 more source

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

Epilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden, Verena Buchecker, Amelie Wagner, Victoria M. Stocker, Liga Zvejniece, Heidrun Potschka   +5 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice

Iranian Journal of Medical Sciences, 2016
Sodium valproate and tomato extract have been studied in different experimental models of epilepsy individually. The aim of the present study was to evaluate the effect of lycopene on the antiepileptic effects of sodium valproate against ...
Vinay Kumar, Sandeep Kumar Sharma, K Nagarajan, Praveen Kumar Dixit   +3 more
doaj  

Phosphorylation of GFAP is associated with injury in the neonatal pig hypoxic-ischemic brain [PDF]

, 2012
Glial fibrillary acidic protein (GFAP) is an intermediate filament protein expressed in the astrocyte cytoskeleton that plays an important role in the structure and function of the cell.
A Lee, BE Lingwood, C Peeters-Scholte, CE Finch, David V. Pow, DM Ferriero, DV Pow, DV Pow, EG Hughes, GA Dienel, H Kosako, H Li, H Tanaka, J Middeldorp, JH Herskowitz, K Morimoto, K Tsujimura, KD Geiger, L Hertz, L Hertz, L Li, LF Eng, LJ Martin, LM Valentim, LT Macnab, M Anderova, M Inagaki, M Inagaki, M Inagaki, M Sekimata, M Takemura, MA Korolainen, MC Toet, MR Cilio, MV Sofroniew, P Lipton, Paul B. Colditz, R Rodnight, Robert K. P. Sullivan, S. Tracey Björkman, SM Sullivan, SM Sullivan, SM Sullivan, SM Sullivan, SM Williams, ST Bjorkman, ST Bjorkman, Stephanie M. Miller, Susan M. Sullivan, SV Sizonenko, T Yano, U Wilhelmsson, Y Matsuoka, Zoe Ireland   +53 more
core   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Ahogamiento incompleto, valoración de la injuria cerebral al ingreso: Terapia Intensiva Pediátrica. Nearly drowning, valuation of the cerebral injury when entering the hospital: Intensive Pediatric Therapy

Revista Médica Electrónica, 2009
Se realizó una investigación descriptiva retrospectiva que incluyó a todos los pacientes que fueron ingresados en el Servicio de Terapia Intensiva del Hospital Eliseo “Noel” Caamaño, en el período comprendido desde junio de 1982 hasta junio ...
Orlando López Torres, Joel Lima Castro, Jorge D Berdalles Milián, Reynol García Montes de Oca   +3 more
doaj  

Natural Products in Epilepsy—the Present Situation and Perspectives for the Future [PDF]

, 2014
More efficacious and better tolerated treatments for epilepsy are clearly needed. Complementary and alternative medicine (CAM) has a long history of use in certain parts of the world and has gained increasing interest over the last decades in Western ...
Ekstein, Dana, Schachter, Steven C.
core   +1 more source