Results 91 to 100 of about 590,200 (259)

The Motives for Moral Credit [PDF]

open access: yes, 2017
To deserve credit for doing what is morally right, we must act from the right kinds of motives. Acting from the right kinds of motives involves responding both to the morally relevant reasons, by acting on these considerations, and to the morally ...
Rozeboom, Grant
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Comparison of Digital and Analogue Behind the Ear Hearing Aids Effectiveness in Treatment of Tinnitus in Elderly Patients of Otolaryngology Centers in Hamadan (2006-2007)

open access: yesپزشکی بالینی ابن سینا, 2009
Introduction & Objective: Tinnitus is one of the most common otologic complaints. This study was designed for evaluation of different kinds of hearing aids effectiveness in treatment of tinnitus in elderly patients in Hamadan.
Faranak Imami   +3 more
doaj  

Revalorized Black Embodiment: Dancing with Fanon [PDF]

open access: yes, 2012
This article explores Fanon's thought on dance, beginning with his explicit treatment of it in Black Skin, White Masks and The Wretched of the Earth.
Hall, Joshua M.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Special Libraries, July-August 1946 [PDF]

open access: yes, 1944
Volume 37, Issue 6https://scholarworks.sjsu.edu/sla_sl_1946/1005/thumbnail ...
Special Libraries Association
core   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dignity and the Phenomenology of Recognition-Respect [PDF]

open access: yes, 2017
What is dignity? My starting point is that dignity is one of those philosophical primitives that admit of no informative analysis. Nonetheless, I suggest, dignity might yield to indirect illumination when we consider the kind of experience we have (or ...
Kriegel, Uriah
core  

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