Results 71 to 80 of about 590,200 (259)
Using Experiments to Foster Innovation and Improve the Effectiveness of Energy Efficiency Programs [PDF]
This paper argues that the establishment of a process designed to manage innovation must be developed in California to foster the creation of needed program improvements and develop new and more effective energy efficiency delivery programs.
Sullivan, Michael J
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Bail Reform for the Eighties: A Reply to Senator Kennedy [PDF]
The Bail Reform Act of 1966 may rank as the most significant legislative reform of the criminal process of this century. A product of the New Frontier and the Great Society, it reflected a broad consensus that society had the ability and the duty to ...
Duke, Steven
core +1 more source
The Morality of Moral Neuroenhancement [PDF]
This chapter reviews recent philosophical and neuroethical literature on the morality of moral neuroenhancements. It first briefly outlines the main moral arguments that have been made concerning moral status neuroenhancements.
Douglas, Thomas
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
International Research Project on Job Retention and Return to Work Strategies for Disabled Workers: Germany [PDF]
[Excerpt] The International Research Project on Job Retention and Return to Work Strategies for Disabled Workers is an initiative of the International Labour Organisation (ILO) and the Global Applied Research and Information Network on Employment and ...
Albrecht, Martin, Braun, Hans
core +1 more source
Some Remarks about the Complexity of Epidemics Management
Recent outbreaks of Ebola, H1N1 and other infectious diseases have shown that the assumptions underlying the established theory of epidemics management are too idealistic. For an improvement of procedures and organizations involved in fighting epidemics,
Brown, André EX +11 more
core +4 more sources
Volatile Decision Dynamics: Experiments, Stochastic Description, Intermittency Control, and Traffic Optimization [PDF]
The coordinated and efficient distribution of limited resources by individual decisions is a fundamental, unsolved problem. When individuals compete for road capacities, time, space, money, goods, etc., they normally make decisions based on aggregate ...
+26 more
core +1 more source

